Identifying early osteoclastic resorptive lesions in feline teeth: a model for understanding the origin of multiple idiopathic root resorption

DeLaurier, April; Boyde, A.; Jackson, Ben; Horton, Michael A.; Price, J. S.

doi:10.1111/j.1600-0765.2008.01123.x

Cited by 27 publications

(30 citation statements)

References 47 publications

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“…Other factors such as developmental defects, trauma, bruxism, environmental exposure, inflammatory reactions, and feline herpes virus 1 (FeHV‐1) have been speculated to be associated with MICRR 2,10,21,25,33‐35 . In the present report, none of the patients received orthodontic treatment or displayed evidence of occlusal trauma or parafunctional habits.…”

Section: Discussionmentioning

confidence: 57%

A Familial Pattern of Multiple Idiopathic Cervical Root Resorption With a 30‐Year Follow‐Up

Neely

Thumbigere‐Math

Somerman

et al. 2016

Journal of Periodontology

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Background Multiple idiopathic cervical root resorption (MICRR) is a rare entity distinct from pathological root resorption that occurs as a result of several local and systemic factors. Methods This report describes a familial pattern of MICRR, including a recently identified case and a 30-year follow-up on previously described cases. Results The previously reported father (95-years) and son (64-years), and the recently affected daughter (61-years), presented noncontributory medical history. The resorptive lesions were asymptomatic, unassociated with any predisposing factors, and were first identified during the fourth to sixth decades of life. All tooth types were affected, with posterior teeth being affected earlier and with greater frequency, however, distal root surfaces were never affected. The resorptive lesions were progressive in nature with additional teeth becoming involved as the condition was followed over time. In many instances, surrounding alveolar bone extended into the existing resorptive defects, but without clinical evidence of ankylosis. Gingival tissues, periodontal probing, and tooth mobility were within normal limits. Micro-computed tomography of extracted teeth demonstrated that the lesions were more extensive than clinically evident and rarely invaded the pulp chamber. Histologically, many resorptive lesions were noted along the cementum surface, with evidence of isolated cemental repair. Management of MICRR focused on restoring damaged root surfaces and extracting teeth with extensive root resorption. Conclusions MICRR is a challenging entity with unknown etiology, and a lack of well-established preventative and management strategies. The familial pattern noted in this report necessitates future studies to investigate the role of genetic components in MICRR development.

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Section: Discussionmentioning

confidence: 57%

A Familial Pattern of Multiple Idiopathic Cervical Root Resorption With a 30‐Year Follow‐Up

Neely

Thumbigere‐Math

Somerman

et al. 2016

Journal of Periodontology

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“…21 It is recognized that in many cat households, there is a lack of stimulus required to maintain the functional integrity of the periodontal ligament, especially for canine teeth. [22][23][24] Limitations of this study were mostly financial, since data was collected retrospectively and used routine preoperative laboratory data analysis, without the possibility to collect other serum laboratory tests. Type 2 TR lesions have been shown to be poorly linked to periodontal variables with TR perhaps more appropriately associated with age and occlusal forces.…”

mentioning

confidence: 99%

Risk Assessment of Feline Tooth Resorption: A Portuguese Clinical Case Control Study

et al. 2013

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Tooth resorption (TR) is one of the most common dental diseases in cats. Determination of risk factors has not yet been fully assessed and, to the best knowledge of the authors, this disease has never been studied in Portuguese cats. The objective of this case-control study was to determine type and distribution of TR lesions, evaluate risk factors, and establish relationships between variables in this disease. The study included data from 71 cats admitted for general anesthesia for various reasons. The cats were randomly selected. The inclusion criteria were availability of clinical history and owner permission. Cats with known oral disease were not excluded from the study. All cats received ultrasonic scaling and polishing of the teeth, a thorough oral examination, and full-mouth radiographs. A strong statistical relation was found between age and TR. The age group of 10 to 15-years showed an increased risk of 6.56 times for TR occurrence compared with the group 0 to 4-years of age. Presence of gingivitis in all index levels was related to an increased risk for TR. No relation was found between age or gingivitis index and lesion type. Mandibular third premolar and molar teeth were most commonly affected by TR, especially for type 1 lesions. Canine teeth were statistically more likely to have type 2 lesions. The trend for the canine teeth to be more affected with type 2 lesions needs further verification.

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“…Feline odontoclastic resorptive lesions affect multiple teeth but are more frequently observed on molar and premolar teeth than on the canines and incisor teeth. 1976; Schlup and Stich, 1982;Reichart et al, 1984), while more recent analyses suggest that resorptive lesions may initiate anywhere on the tooth surface (Harvey et al, 2004;DeLaurier et al, 2009). In addition, these lesions are often symmetrical and therefore do not seem to occur at random (Ingham et al, 2001), which suggests that there is a predilection site on different tooth regions.…”

Section: Introductionmentioning

confidence: 99%

Identifying enamel diffusion properties in feline teeth affected with resorptive lesions

Živković¹,

Todorović²,

Tihaček-Šojić³

et al. 2011

Acta vet. (Beogr.)

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Various factors have been suggested in the pathogenesis of feline resorptive lesions, such as periodontal disease, dietary factors, mechanical stress, developmental tooth defects, breed and viral disease, although none of these factors have been definitively proven to be the direct cause. It was recently published that normally enamel in cats is significantly thinner at the cemento-enamel junction, and both enamel and dentine are significantly less mineralized than elsewhere on the tooth. However, it is still unclear what anatomical features of the tooth surface are associated with a predisposition for resorptive lesions, and what is the initiating cause for the clastic activity afterwards. The present study was undertaken with the aim to describe enamel properties of transport and distribution of organic molecules in intact feline teeth and teeth affected with resorptive lesions. The results indicate that damaged enamel is prone to a greater bilateral diffusion process, leading to continuous disruption of the enamel structure. Also, teeth that are subjected to occlusal stress are at greater risk of destruction because micro fractures produce disarrangements in feline dental tissue diffusion homeostasis. The relationship between these features with feline dental resorptive lesions requires further studies

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Identifying early osteoclastic resorptive lesions in feline teeth: a model for understanding the origin of multiple idiopathic root resorption

Cited by 27 publications

References 47 publications

A Familial Pattern of Multiple Idiopathic Cervical Root Resorption With a 30‐Year Follow‐Up

A Familial Pattern of Multiple Idiopathic Cervical Root Resorption With a 30‐Year Follow‐Up

Risk Assessment of Feline Tooth Resorption: A Portuguese Clinical Case Control Study

Identifying enamel diffusion properties in feline teeth affected with resorptive lesions

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