2024
DOI: 10.2903/sp.efsa.2024.en-9099
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Identifying in vitro toxicity testing approaches for (novel) proteins in the context of food and feed risk assessment

Louis‐Marie Cobigo,
Denis Habauzit,
Kahina Mehennaoui
et al.

Abstract: This report documents the outcomes of the EFSA procurement (OC/EFSA/NIF/2022/01) aimed at identifying in vitro toxicity testing approaches for (novel) proteins in the context of food and feed safety assessment. In the present report, we present an integrated testing strategy for the evaluation of toxicity of novel/toxic proteins. A text‐mining approach was used to create a literature database of toxic outcomes associated with toxic proteins retrieved from the UniProt KB database using the search term “Toxin ac… Show more

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