2017
DOI: 10.1016/j.bpj.2016.11.841
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Identifying Peptide-Peptide Interactions with Lysenin Nanopores

Abstract: Bacteriophage T4 is one of the most common and complex tailed viruses from the family Myoviridae, and it infects E. coli using a highly efficient contractile genome delivery machine. Phage T4 possesses a multi-protein capsid containing the genomic DNA and a long contractile tail assembly that consists of a rigid tail tube surrounded by a six helical-stranded sheath. The tail assembly transmits the genomic DNA from the capsid to the host during injection. While the atomistic structure of phage T4 has been studi… Show more

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