Identifying risk factors associated with acquiring measles in an outbreak among age-appropriately vaccinated school children: a cohort analysis

Abstract

The reason for intense measles activity in one class was not established. Although a concurrent investigation into cold chain and vaccine stock management did not identify a cause for the high relative risk of measles in children vaccinated, recommendations were made for improving cold chain and vaccine stock management in General Practices.

Trends in mumps incidence and first dosage of MMR vaccine coverage in Montenegro from 2009 to 2018

“…Also, the risk was significantly higher for those who received the last dose of MMR vaccine 5 or more years ago. This has actualized the issue of the MMR vaccine effectiveness in protecting against mumps and considering changing the vaccine calendar (18)(19)(20)(21)(22)(23)(24).…”

“…Some studies have suggested the possibility (and some have proven) that there is a difference between the genotype of the circulating Mumps virus and that in MMR vaccines, and a potential cold chain disruption was previously recognized as a potential cause for the lack of protective effect of the MMR vaccine and which is essential for this vaccine to be maintained (stored at +2 to + 8° C, in a dark place for up to one hour before administration). It should be noted that genotyping of the circulating Mumps virus is not done routinely, and cold chain surveillance is an obligation of the services that are in charge of implementing national immunization programs (18)(19)(20)(21)(22)(23)(24).…”