Identifying Risk Factors for Massive Right Ventricular Dilation in Patients With Repaired Tetralogy of Fallot

Cochran, Clinton D.; Yu, Sunkyung; Gakenheimer‐Smith, Lindsey; Lowery, Ray; Lu, Jimmy C.; Mahani, Maryam Ghadimi; Agarwal, Prachi P.; Dorfman, Adam L.

doi:10.1016/j.amjcard.2019.12.016

Cited by 6 publications

(1 citation statement)

References 48 publications

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“…11 Overall non-Hispanic Black patients had an exacerbated decrease in survival rates with any tricuspid valve defects. 11,12 Hispanic children however had a higher mortality risk for hypoplastic left heart syndrome with a hazard ratio of 1.51. 11,12 Further research should be conducted to assess whether maternal race/ethnicity plays a role in the severity of congenital heart defect.…”

Section: Resultsmentioning

confidence: 98%

Racial and socioeconomic disparities in congenital heart surgery: A research article

Richardson¹,

Itua

Duong

et al. 2021

Journal of Cardiac Surgery

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Background: Though the modern era has proven to be reassuring with the advancement of perioperative care leading to improved survival, congenital heart disease (CHD) continues to underscore its significance in the lives of newborns and families worldwide. Particularly, CHD has disproportionately afflicted vulnerable minorities such as Black and Hispanic populations from the standpoint of ethnic disparities in mortality following heart surgery, increased resource utilization, and longer durations of stay. This study aims to identify and provide insight regarding the relationships between the aforementioned factors to develop targeted strategies of intervention to mitigate the outcomes for patients of these specific populations.Methods: Free, current peer-reviewed literature from databases such as the

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Section: Resultsmentioning

confidence: 98%

Racial and socioeconomic disparities in congenital heart surgery: A research article

Richardson¹,

Itua

Duong

et al. 2021

Journal of Cardiac Surgery

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Kardiale Magnetresonanztomographie

2020

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Zusammenfassung Hintergrund Durch die Entwicklung robuster Techniken und deren umfassender Validierung hat sich die kardiale Magnetresonanztomographie (CMR) in ihrem knapp 25-jährigen klinischen Einsatz ein breites Indikationsspektrum erarbeitet. Die Erfassung kardialer Volumina und systolischer Ventrikelfunktion sowie die Charakterisierung fokaler Myokardnarben sind heute Teil der CMR-Standard-Bildgebung. Zuletzt haben die Einführung beschleunigter Bildakquisitionstechnologien, die neuen Bildgebungsmethoden des myokardialen T1- und T2-Mappings und der 4‑D-Flussmessungen sowie die neue Postprocessing-Technik des myokardialen Feature-Trackings an Relevanz gewonnen. Methode Diese Überblicksarbeit basiert auf einer umfassenden Literaturrecherche in der PubMed-Datenbank zu neuen CMR-Techniken und ihrer klinischen Anwendung. Ergebnisse und Schlussfolgerung Dieser Artikel zeigt eine Übersicht über die neuesten technischen Entwicklungen im Bereich der CMR sowie deren Anwendungsmöglichkeiten anhand der wichtigsten klinischen Fragestellungen.

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Health Disparities in Exercise Performance in Patients with Repaired Tetralogy of Fallot

Jones,

Xiao,

Williamson

et al. 2024

Pediatr Cardiol

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Black patients with tetralogy of Fallot (TOF) have higher mortality than White patients. Health disparities related to other patient-important outcomes, such as exercise performance, have not been studied in this population. We aimed to determine if there are racial disparities related to exercise performance in patients with TOF and to investigate possible mediators of those disparities. We conducted a retrospective single center study of patients aged 8–25 years with repaired TOF who completed maximal cardiorespiratory exercise tests between 2007 and 2020. The primary outcome was percent predicted oxygen consumption at peak exercise. We used linear regression to determine if race was associated with exercise performance. We used mediation analysis to investigate insurance coverage and neighborhood Child Opportunity Index as possible mediators of this relationship. The study cohort included 163 patients with TOF (136 non-Hispanic/Latinx White and 27 non-Hispanic/Latinx Black). In multivariable analysis, Black patients had a lower percent predicted peak oxygen consumption than White patients by 6.71 percentage points (95% CI − 12.71, − 0.70; p = 0.029). Mediation analysis revealed that the indirect effect of race through insurance coverage accounted for 34.1% of the decrease in exercise performance. Child Opportunity Index was not a statistically significant mediator. Black patients with TOF had worse exercise performance than White patients. Differences in insurance coverage accounted for a significant portion of this difference. Exercise performance is an important outcome for patients with TOF, and further investigation is needed to better understand this disparity and develop interventions to address it.

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Identifying Risk Factors for Massive Right Ventricular Dilation in Patients With Repaired Tetralogy of Fallot

Cited by 6 publications

References 48 publications

Racial and socioeconomic disparities in congenital heart surgery: A research article

Racial and socioeconomic disparities in congenital heart surgery: A research article

Kardiale Magnetresonanztomographie

Health Disparities in Exercise Performance in Patients with Repaired Tetralogy of Fallot

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