Recently, Kim-Kim (2016 studied simmetric identities of higher-order degenerate Bernoulli and Euler polynomials which were defined by Carlitz (1979). In this paper, we define the higher-order deformed degenerate Bernoulli and Euler polynomials which are modified the higher-order degenerate Bernoulli and Euler polynomials. We also investigate some interesting identities for the the higher-order deformed degenerate Bernoulli and Euler polynomials.