Idiopathic Anaphylaxis and Histamine Intolerance

Ivković‐Jureković, Irena

doi:10.1111/pai.12438

Cited by 5 publications

(8 citation statements)

References 17 publications

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“…An interesting case series by Ivkovic-Jurekovich in 20159 describes three patients with a clinical picture suggestive of histamine intolerance associated with IA. Interestingly, all three patients were found to have a positive autologous serum tests (ASST), but a histamine release test was negative and the presence of circulating auto-antibodies against IgE and FcεRIα could not be confirmed.…”

Section: Resultsmentioning

confidence: 99%

“…Frequent episodes are defined as at least two episodes in the preceding two months or at least six episodes in the preceding year 29. For patients with frequent IA, all studies in this review report a treatment of continuous prednisone at a dose of 20 to 80 mg,9–11,21,22,29 antihistamines (e.g. cetirizine 10 mg)9,13,14,30 and sympathomimetics (e.g.…”

Section: Resultsmentioning

confidence: 99%

“…Frequent episodes are defined as at least two episodes in the preceding two months or at least six episodes in the preceding year. Although several case series have been published regarding IA,8,9 few reviews have focused on the diagnosis and management strategies of IA. In this study, we aim to present a systematic review of the literature published in the past 22 years regarding IA in the adult and pediatric population with a focus on diagnosis and management strategies pertinent for the Emergency Room (ER) physician.…”

Section: Introductionmentioning

confidence: 99%

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<p>Management Strategies Of Idiopathic Anaphylaxis In The Emergency Room: Current Perspectives</p>

Gabrielli

Schryver

et al. 2019

OAEM

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BackgroundIdiopathic anaphylaxis (IA) is a diagnosis of exclusion and represents a major diagnostic and management challenge. There are no current guidelines for diagnosis and management of IA. We aim to present a systematic review of the literature on adult and pediatric IA.MethodsWe conducted a systematic review of original articles published in the past 22 years regarding diagnosis and management strategies of adult and pediatric IA.ResultsThe current proposed diagnostic approach and treatment regimens are based on a few small studies. Future large-scale studies are required. IA is a diagnosis of exclusion and should be made only after extensive evaluation excludes potential anaphylaxis triggers as well as non-allergic conditions with a similar presentation. There is currently no diagnostic consensus for IA. Furthermore, the current proposed treatment regimens are limited and rely on prophylactic treatment with antihistamines and prednisone for patients with frequent episodes. However, daily treatment with systemic steroids has well-recognized serious adverse effects. More recently, the use of biologics was suggested to benefit patients with IA, although the optimal management protocol is not yet established.ConclusionFuture studies are needed to optimize diagnosis and treatment strategies in adult and pediatric cases of IA. Omalizumab may be a promising novel therapeutic option for adult and pediatric IA.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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<p>Management Strategies Of Idiopathic Anaphylaxis In The Emergency Room: Current Perspectives</p>

Gabrielli

Schryver

et al. 2019

OAEM

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“…70,71 A low-histamine diet (ie, avoidance of fermented dairy products and fermented vegetables) is sometimes advised, but no evidence to support this practice for IA has been reported. 72 Although considered as potential allergens in the past, that artificial food coloring, dyes, or preservatives induce anaphylaxis is unlikely. Attempts to reproduce symptoms on oral challenge with such food additives as metabisulfite and monosodium glutamate have generally been negative.…”

Section: Hidden Allergenmentioning

confidence: 99%

Idiopathic anaphylaxis yardstick

Carter

Akin

Castells

et al. 2020

Annals of Allergy, Asthma & Immunology

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Anaphylaxis is considered idiopathic when there is no known trigger. The signs and symptoms of idiopathic anaphylaxis (IA) are identical to those of anaphylaxis because of a known cause and can include cutaneous, circulatory, respiratory, gastrointestinal, and neurologic symptoms. Idiopathic anaphylaxis can be a frustrating disease for patients and health care providers. Episodes are unpredictable, and differential diagnosis is challenging. Current anaphylaxis guidelines have little specific guidance regarding differential diagnosis and long-term management of IA. Therefore, the objective of the Idiopathic Anaphylaxis Yardstick is to use published data and the authors' combined clinical experience to provide practical recommendations for the diagnosis and management of patients with IA.

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“…Hedef organda artmış hassasiyet de düşünülmekle beraber, histamin ile yapılan çalışmalarda bu gösterilememiştir 8,34 . Herediter ya da akkiz anjioödem hastalığını dışlamak için C1 esteraz inhibitör, C3, C4, CH50 düzeylerine bakılır.…”

Section: Histamin Intoleransıunclassified

Idiopathic anaphylaxis: Diagnosis and Treatment.

Özdemir¹

2018

MMJ

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Bu derleme makalesinde, öncelikle anafilaksinin tanımı, sıklığı, tipleri ve tanı kriterlerinden söz edildikten sonra idiopatik anafilaksi (İA)'nin tanım, teşhisi, epidemiyolojisi, etyo-patogenezi ve ayırıcı tanısı anlatılacak daha sonra tedavisi ile devam edilecektir. Anafilaksi bilindiği gibi tanısı kolay olmakla beraber, kafa karıştırıcı olabilen, yine zamanında müdahale edilmezse hızlıca şoka doğru ilerleyen ve ölümcül olabilen bir hastalıktır. Bu yüzden iyi bilinerek çabuk ve doğru olarak tanınmalı gecikmeden doğru girişimlerde bulunulmalıdır.

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Idiopathic Anaphylaxis and Histamine Intolerance

Cited by 5 publications

References 17 publications

<p>Management Strategies Of Idiopathic Anaphylaxis In The Emergency Room: Current Perspectives</p>

<p>Management Strategies Of Idiopathic Anaphylaxis In The Emergency Room: Current Perspectives</p>

Idiopathic anaphylaxis yardstick

Idiopathic anaphylaxis: Diagnosis and Treatment.

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