Idiopathic benign biliary strictures in surgically resected patients with presumed cholangiocarcinoma

Baskin-Bey, Edwina S.; Devarbhavi, Harshad; Nagorney, David M.; Farnell, Michael B.; Donohue, John H.; Sanderson, Schuyler O.; Stadheim, Linda M.; Gores, Gregory J.

doi:10.1080/13651820500292954

Cited by 5 publications

(6 citation statements)

References 17 publications

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“…Our study demonstrates that patients with benign biliary strictures are likely to be women. This was in consistent with the findings of Baskin-Beyet al 4 This study demonstrates that patients with benign biliary strictures are more likely to have Bismuth-Corlette type II, followed by type III, I and IV. In contrast to this, in a study done by Verbeek et al type III strictures were seen in most of the patients.…”

Section: Discussionsupporting

confidence: 93%

“…In contrast to this, in a study done by Verbeek et al type III strictures were seen in most of the patients. 5 However our data were similar to those of Baskin-Bey et al and Hadjis et al 4,6 In their study predominantly type I and II strictures were noticed. These findings suggest that strictures below the biliary confluence are likely to be benign rather than malignant.…”

Section: Discussionsupporting

confidence: 91%

“…Similarly, in a study done by Baskin-Bey et al, 8 of 12 patients underwent HJJ. 4 The complication rate in revision surgeries ranges from 11-33%. 13,14 In our series, the overall complication rate was 51%.…”

Section: Discussionmentioning

confidence: 99%

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Clinicopathological study and management of benign biliary stricture

Paul¹,

Das²

2019

Int Surg J

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Background: A stricture of the biliary tract can be one of the most difficult challenges that a surgeon can face. If unrecognized or managed improperly life threatening complications may develop. The goal of this study is to describe the most appropriate management for benign biliary stricture.Methods: This was a prospective study done on 29 patients diagnosed with benign biliary stricture. Complete biochemical profile, USG-whole abdomen, and other radiological investigations were done to evaluate the detailed etiological condition of the patient. Appropriate surgical intervention was implemented in the patients. Related complications and clinical outcome was observed during the follow up period of 2 years.Results: Mean age of the study population was 45 years (ranging from 22-62 years). Female preponderance was seen in the study. USG of abdomen was done in all the patients (100%). Overall complications were observed in 15 patients.Conclusions: Benign biliary strictures occur more often in women. Complications and clinical outcome depends on the time of diagnosis, matured clinical judgment and appropriate surgical intervention. Hepaticojejunostomy (HJJ) was the common surgical procedure adopted in in 23 patients.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Clinicopathological study and management of benign biliary stricture

Paul¹,

Das²

2019

Int Surg J

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“…Even when IgG4-related diseases are excluded, approximately 10% of patients who present with what appears to be pCCA are found to have benign disease during surgery. 63 …”

Section: Perihilar Cholangiocarcinomamentioning

confidence: 99%

Classification, Diagnosis, and Management of Cholangiocarcinoma

Razumilava

Gores

2013

Clinical Gastroenterology and Hepatology

266

227

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Cholangiocarcinomas (CCAs) are tumors that develop along the biliary tract. Depending on their site of origin, they have different features and require specific treatments. Classification of CCAs into intrahepatic, perihilar, and distal subgroups has helped standardize the registration, treatment, and study of this lethal malignancy. Physicians should remain aware that cirrhosis and viral hepatitis B and C are predisposing conditions for intrahepatic CCA. Treatment options under development include locoregional therapies and a chemotherapy regimen of gemcitabine and cisplatin. It is a challenge to diagnose perihilar CCA, but an advanced cytologic technique of fluorescence in situ hybridization for polysomy can aid in diagnosis. It is important to increase our understanding of the use of biliary stents and liver transplantation in the management of perihilar CCA, as well as to distinguish distal CCAs from pancreatic cancer, because of different outcomes from surgery. We review advances in the classification, diagnosis, and staging of CCA, along with treatment options.

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“…Unfortunately, tissue diagnosis is difficult given limited access to the bile duct, and the highly desmoplastic nature of biliary tract cancers. Negative biopsies and brushings, therefore, do not exclude bile duct cancers [16]. The distinction between malignant and inflammatory strictures is confounded in PSC as the inflammation associated with this disorder complicates cytologic assessment.…”

Section: See Article Pages 568-574mentioning

confidence: 99%