Idiopathic Chondrolysis of the Hip ( ICH): Report of three Cases

Abstract

Idiopathic Chondrolysis of the Hip (ICH) is a rare condition, occurring mostly in black female adolescence. It is characterized by the rapidly progressive destruction of articular cartilage in the hip joint resulting in premature degeneration and subsequent joint arthrosis. We report three cases of ICH: a 13-year old boy presented with left knee pain, an 11-year old girl with right hip pain and a 12-year old girl with right thigh pain. All of them had the same characteristic radiographic findings. The initial treatment was started conservatively. Surgical treatment was performed in one patient in order to confirm diagnosis and correct deformity.

Society of Toxicologic Pathology Nonhuman Primate Special Interest Group: Idiopathic Femoral Head Chondrolysis in Nonclinical Research Macaques

“…5 It is a diagnosis of exclusion, and is made only in the absence of other inciting factors such as a history of trauma, clinical evidence of infection, or diagnostic findings supportive of other known disease entities. 6 Several causes have been speculated, including an underlying genetic predisposition, abnormal chondrocyte metabolism or chondrolytic enzyme release, and autoimmune-mediated destruction of the articular cartilage; however, none have been definitively confirmed. 4 There is no known treatment, and disease management is focused upon management of clinical symptoms with analgesics and physical therapy, or arthroplasty with soft tissue release in advanced cases that do not respond to conservative management.64 Other differential diagnoses for hip chondrolysis in primates include Legg-Calve-Perthes disease, pigmented villonodular synovitis, osteoarthritis, septic arthritis, rheumatoid arthritis, and traumatic injury.…”

MRI features and treatment options for Idiopathic Chondrolysis of the Hip (ICH) in children. Outcomes of a systematic review.

“…There were 45 subtotal/partial capsulectomies ( 4-5, 14, 18, 21, 26, 29, 38), 18 THA (4-5, 12, 18, 22), 14 open arthrotomies with or without biopsy and debridement (14, 16-17, 19-20, 24, 33), ve arthrodiastasis ( 5,15,32) , ve arthrodesis (18-19, 21, 23,) three osteotomies (16,19,29), three excision arthroplasties (19,21), one each hanging hip operation, mould, cup and resurfacing arthroplasties (14,19,21). Tenotomies of muscle and soft tissue releases were either isolated or combined with other surgical procedures in 25 hips (14,(17)(18)22,26,(29)(30). Arthroscopy with or without associated procedures of labral debridement, abrasion chondroplasty, cartilage, and joint debridement with or without synovectomy was done for seven hips (11,29,31).…”

“…We excluded secondary chondrolysis of the hip due to Slipped capital femoral epiphysis (SCFE), Perthes disease, and inciting events (Table 1). However, ICH cases from mixed studies meeting inclusion criteria were included in this review (4,5,11,(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24). A mixed study for ICH was identi ed when it described heterogeneous treatment methods or reported it as a cause of arthritis.…”