Idiopathic elevated episcleral venous pressure and open-angle glaucoma

Rhee, Douglas J.; Gupta, Meenakashi; Moncavage, Melissa B; Moster, Mark L.; Moster, Marlene R.

doi:10.1136/bjo.2007.126557

Cited by 43 publications

(68 citation statements)

References 21 publications

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“…Previous studies suggested that the episcleral venous pressure (EVP), which is part of the IOP Goldmann equation, is higher in glaucomatous eyes [32,33]. In contrast to glaucoma patients, the EVP in our model is likely very low without an existing blood circulation.…”

Section: Discussionmentioning

confidence: 80%

Outflow Enhancement by Three Different ab Interno Trabeculectomy Procedures in a Porcine Anterior Segment Model

Dang¹,

Wang²,

Shah³

et al. 2018

Preprint

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Objective: To evaluate three different microincisional ab interno trabeculectomy procedures in a porcine eye perfusion model. Methods:In perfused porcine anterior segments, 90 degrees of trabecular meshwork (TM) were ablated using the Trabectome (T; n=8), Goniotome (G; n=8), or Kahook device (K; n=8). After 24 hours, additional 90 degrees of TM were removed. Intraocular pressure (IOP) and outflow facility were measured at 5 µl/min and 10 µl/min perfusion to simulate an elevated IOP. Structure and function were assessed with canalograms and histology.Results: At 5 µl/min infusion rate, T resulted in a greater IOP reduction than G or K from baseline (76.12% decrease versus 48.19% and 47.96%, P=0.013). IOP reduction between G and K was similar (P=0.420). Removing another 90 degrees of TM caused an additional IOP reduction only in T and G but not in K. Similarly, T resulted in the largest increase in outflow facility at 5 µl/min compared with G and K (first ablation: 3.41 times increase versus 1.95 and 1.87; second ablation: 4.60 versus 2.50 and 1.74) with similar results at 10 µl/min (first ablation: 3.28 versus 2.29 and 1.90 (P=0.001); second ablation: 4.10 versus 3.01 and 2.01 (P=0.001)). Canalograms indicated circumferential flow beyond the ablation endpoints.Conclusions: T, G and K significantly increased the outflow facility. In this model, T had a larger effect than G and K.

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Section: Discussionmentioning

confidence: 80%

Outflow Enhancement by Three Different ab Interno Trabeculectomy Procedures in a Porcine Anterior Segment Model

Dang¹,

Wang²,

Shah³

et al. 2018

Preprint

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“…Certain complications are more likely to occur in the setting of Radius-Maumenee syndrome, such as choroidal effusion, shallowing of the anterior chamber and expulsive haemorrhage. Choroidal effusion tends to occur at somewhat higher than expected IOP levels (Rhee et al 2009). One of our two patients developed uveal effusion at a pressure of 8 mmHg; the effusion was completely resolved by day 5 after the surgery.…”

mentioning

confidence: 95%

“…Other causes include large vessel venous obstruction (venous sinus thrombosis and superior vena cava syndrome), Sturge-Weber syndrome, scleritis, thyroid-related orbitopathy and orbital tumours or orbital varices (Radius & Maumenee 1978;Rhee et al 2009). …”

mentioning

confidence: 99%

“…The syndrome was originally described by Minas & Podos (1968 venous pressure, is not present in all patients with Radius-Maumenee syndrome (Foroozan et al 2003;Rhee et al 2009). Additional signs and symptoms typical for carotid-cavernous fistula such as a pulsatile tinnitus, chemosis, proptosis, decreased ocular motility, diplopia, decreased visual acuity, headache and retinal venous congestion are absent in the case of Radius-Maumenee syndrome.…”

mentioning

confidence: 99%

“…About 25 patients with RadiusMaumenee syndrome have been described in the English literature (Rhee et al 2009). Radius and Maumenee suggested congenital anomaly of the episcleral vessels as one possible aetiology (Radius & Maumenee 1978).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Challenging cases of ocular injection and increased intraocular pressure

Vandekerckhove

Kestelyn

2013

Acta Ophthalmologica

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Radius‐Maumenee syndrome: A case series with a long‐term follow‐up

Elksne

Steiner

Hohensinn

et al. 2023

Clinical Case Reports

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The aim of the case series is to highlight the surgical challenges experienced like failed intervention, choroidal effusion, a postoperative cystoid macular oedema, and describe treatment options for Radius‐Maumenee syndrome. Authors reported on 3 bilateral cases of Radius‐Maumenee syndrome which underwent medical treatment, trabeculectomy with Mitomycin C, implantation with XEN45, Ahmed glaucoma valve, Baerveldt glaucoma implant, and cyclophotocoagulation.

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Idiopathic elevated episcleral venous pressure and open-angle glaucoma

Cited by 43 publications

References 21 publications

Outflow Enhancement by Three Different ab Interno Trabeculectomy Procedures in a Porcine Anterior Segment Model

Outflow Enhancement by Three Different ab Interno Trabeculectomy Procedures in a Porcine Anterior Segment Model

Challenging cases of ocular injection and increased intraocular pressure

Radius‐Maumenee syndrome: A case series with a long‐term follow‐up

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