Idiopathic Focal Ventricular Tachycardia

Issa, Ziad F.; Miller, John M.; Zipes, Douglas P.

doi:10.1016/b978-0-323-52356-1.00023-2

Cited by 2 publications

(1 citation statement)

References 94 publications

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“…PVC idiopatik dan ventrikel takikardia pada pasien dengan struktur jantung yang normal terjadi pada sekitar 10% dari seluruh pasien dengan aritmia ventrikel. (1) Mayoritas PVC idiopatik berasal dari right or left ventricular outflow tracts dan juga dari aortic sinuses of Valsalva. PVC dengan kategori High burden dapat menyebabkan kardiomiopati yang ditandai dengan berkurangnya Fungsi Sistolik (EF) ventrikel kiri.…”

Section: Pendahuluanunclassified

A 3-Dimensional Ablation At Patient With Tachycardia Right Ventricular Outflow Track (RVOT) Origin: First Experienced in Saiful Anwar General Hospital Malang

Cik,

Rizal

2024

JK-RISK

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Background: Premature ventricular complexes (PVCs) occur commonly in general population. It can occur in patient without structural heart disease as well as those with any form of cardiac disease. Commonly PVCs are asymptomatic, but in patients with frequent PVCs causing palpitations, syncope or dizziness, easily to fatigue, or shortness of breath. PVCs has been connected with a more than two-fold higher risk of cardiovascular events including stroke, mortality and also associated with arrhythmias or cardiomyopathy. Medications can be used to suppress PVCs but when drug therapy is ineffective, PVC ablation is reasonable to eliminate symptoms and treat or prevent PVC-induced cardiomyopathy. Case Presentation: A hypertension and menopause, 57-year-old woman, frequently complained about palpitation with shortness of breath, dizziness and sometimes near syncope since 2017, occurring both at rest and with mild activities. After serial examinations, found Frequent PVC (39%) with RVOT-Origin and reduced ejection fraction (EF 48%), then conclude with Suspect Tachycardia Induced cardiomyopathies. She performs cardiac electrophysiological study and continue with 3-Dimentional Ablation with Radiofrequency (RFA) at RVOT in Saiful Anwar Hospital, that is The First 3-Dimension Ablation in East Java. 1 year follow up shows no recurrency and successful to improve quality of life of the patient Discussion: According to guideline, catheter ablation is class I recommendation for patients with symptomatic outflow tract ventricular arrhythmias if medications are ineffective, not tolerated, or patient’s choose Conclusion: Three-Dimensional Ablation at patient with Right Ventricular Outflow Track Tachycardia, can successfully eliminate PVCs with no recurrency in 1 year follow-up.

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Section: Pendahuluanunclassified

A 3-Dimensional Ablation At Patient With Tachycardia Right Ventricular Outflow Track (RVOT) Origin: First Experienced in Saiful Anwar General Hospital Malang

Cik,

Rizal

2024

JK-RISK

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Effect of carvedilol on premature ventricular complexes originating from the ventricular outflow tract

et al. 2020

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Background Carvedilol is one of the most effective beta-blockers in reducing ventricular tachyarrhythmias and mortality in patients with heart failure. One of the possible antiarrhythmic mechanisms of carvedilol is the suppression of store overload-induced Ca2+ release, especially for the triggered activity. Objectives Premature ventricular complex (PVC) originating from the ventricular outflow tract (OT) is the most common form of idiopathic PVC, and its main mechanism is related to triggered activity. We evaluate the efficacy of carvedilol to suppress the OT PVC. Methods The electronic medical records at our hospital were screened to identify OT PVC patients treated with carvedilol. Clinical, electrocardiographic, and Holter monitoring studies were reviewed. Results A total of 25 patients who underwent Holter monitoring before and after carvedilol administration were found and enrolled. The mean age of the patients was 54.9 ± 13.9 years, and the mean dose of carvedilol was 18.2 ± 10.2 mg (sustained release formulation, 8/16/32 mg). The 24-h burden of PVC in 18 (72%) of 25 patients was significantly reduced from 12.2 ± 9.7% to 4.4 ± 6.7% (P = 0.006). In seven patients, the burden of PVC was changed from 7.1 ± 6.1% to 9.8 ± 8.4% (P = 0.061). There was no difference in age, carvedilol dose, duration of treatment, ventricular function, and left atrial size between responding and non-responding groups. Conclusion In this retrospective pilot study, treatment with carvedilol showed PVC suppression in 72% of patients. Now, we are conducting a prospective, randomized, multicenter study to evaluate the effect of carvedilol on OT PVC (Clinical trial registration: FOREVER trial, Clinical-Trials.gov: NCT03587558).

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Idiopathic Focal Ventricular Tachycardia

Cited by 2 publications

References 94 publications

A 3-Dimensional Ablation At Patient With Tachycardia Right Ventricular Outflow Track (RVOT) Origin: First Experienced in Saiful Anwar General Hospital Malang

A 3-Dimensional Ablation At Patient With Tachycardia Right Ventricular Outflow Track (RVOT) Origin: First Experienced in Saiful Anwar General Hospital Malang

Effect of carvedilol on premature ventricular complexes originating from the ventricular outflow tract

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