Idiopathic Gingival Fibromatosis Rehabilitation: A Case Report with Two-Year Followup

Abstract

Gingival enlargements are quite common and may be either inflammatory, noninflammatory, or a combination of both. Gingival hyperplasia is a bizarre condition causing esthetic, functional, psychological, and masticatory disturbances of the oral cavity. Causes of gingival enlargement can be due to plaque accumulation, due to poor oral hygiene, inadequate nutrition, or systemic hormonal stimulation (Bakaeen and Scully, 1998). It can occur as an isolated disease or as part of a syndrome or chromosomal abnormality. A progressive fibrous enlargement of the gingiva is a facet of idiopathic fibrous hyperplasia of the gingiva (Carranza and Hogan, 2002; Gorlin et al., 1976). It is described variously as fibromatosis gingivae, gingivostomatitis, hereditary gingival fibromatosis, idiopathic fibromatosis, familial elephantiasis, and diffuse fibroma. We present a case of idiopathic gingival fibromatosis with its multidisciplinary approach of management.

Gene expression profiling and bioinformatics analysis of hereditary gingival fibromatosis

“…Gingival fibromatosis (GF) is a rare condition of gingival overgrowth, characterized by a slowly progressive, benign, localized or generalized fibrous enlargement of maxillary and mandibular keratinized gingiva (1)(2)(3). GF may co-exist with various genetic syndromes, such as Rutherfurd syndrome, Cowden syndrome, Zimmerman-Laband syndrome, Murray-Puretic syndrome and hyaline fibromatosis syndrome, or occurs as an apparent isolated trait as non-syndromic hereditary GF (HGF) (1,(4)(5)(6).…”

Diode Laser Versus Scalpel in the Treatment of Hereditary Gingival Fibromatosis in a 6-Year Old Boy

“…1,2 It can be an isolated disease 3 or part of many syndromes such as Zimmerman-Laband, Murray-Puretic-Drescher, Rutherfurd, and Cowden. 4 It equally affects both genders with an incidence of 1 in 750,000.…”

“…2 The constant enlargement of the tissues can eventually lead to arch deformity and can become painful once the tissues cover the occlusal surfaces of the molars. 1 The affected gingiva appears as a pinkish non-hemorrhagic tissue with a firm consistency. 1 A multitude of treatment procedures have been described in the literature and can be summed into two main modalities: the surgical and the laser assisted resection of the hyperplastic gingiva.…”

Complete oral rehabilitation of a patient with hereditary gingival fibromatosis: A clinical report

“…The gingiva is pink, firm, fibrotic, with abundant stippling. [4][5][6][7][8] The onset of HGF usually occurs with the eruption of the permanent teeth but also can occur with the eruption of the primary teeth and, very rarely, is present at birth. 3,9 It may cover the clinical crown of the dentition and compromise the affected individual esthetically, functionally, and psychologically, and can interfere with normal mastication and tooth eruption.…”

“…3,9 It may cover the clinical crown of the dentition and compromise the affected individual esthetically, functionally, and psychologically, and can interfere with normal mastication and tooth eruption. 4 Treatments have ranged from conservative to surgical procedures to extraction of all teeth and reduction of the alveolar bone. Because of the high recurrence rate of the condition, most clinical reports discuss the necessity for repeated surgical excision of the tissue to restore the gingival contours.…”