Idiopathic granulomatous mastitis, erythema nodosum and bilateral ankle arthritis in an Iranian woman

Abstract

SUMMARYHere we report a case of idiopathic granulomatous mastitis (IGM) associated with erythema nodosum (EN) and ankle arthritis. The skin, joint and mammary symptoms improved with corticosteroid. Coincidence of granulomatous mastitis, EN and arthritis is a rare feature. BACKGROUND

Case of erythema nodosum associated with granulomatous mastitis probably due to Corynebacterium infection

“…Although EN has been reported to be associated with a variety of disorders, association of EN with GM is very rare. The first case of EN associated with GM was described in 1987, and a total of nine cases have been reported so far in the English‐language published work . No Corynebacterium spp.…”

“…The first case of EN associated with GM was described in 1987, 7 and a total of nine cases have been reported so far in the English-language published work. [7][8][9][10][11][12][13][14] No Corynebacterium spp. were detected in any of these cases, and in most of them, both lesions of EN and GM were successfully treated with systemic corticosteroids.…”

An Unusual Cause of Oligoarthritis and Erythema Nodosum: Idiopathic Granulomatous Mastitis

“…4,5 Arthritis accompanying IGM regresses concurrently with resolution of IGM, which suggests that arthritis in these cases was the result of a reactive process. 6,8,10 Mild IGM usually resolves spontaneously with drainage. Resolution time may prolong up to 9 to 12 months.…”

“…[4][5][6][7][8][9][10] Two of these reports were associated with pregnancy and lesions had appeared in third trimester. 4,5 Arthritis accompanying IGM regresses concurrently with resolution of IGM, which suggests that arthritis in these cases was the result of a reactive process.…”

“…3 It has been rarely associated with oligoarthritis and erythema nodosum (EN) in the literature. [4][5][6][7][8][9][10] In this article, we discuss the diagnostic, clinical, and therapeutic approach to a unique case with granulomatous mastitis, EN, and arthritis that may be of interest to clinicians who are not readily familiar with this condition.…”