“…Most studies to date have demonstrated ele vations in free or non-SHBG-bound T in IH when total T is normal because the binding capacity of SHBG is lowered. [21][22][23][24][25] Although it has been suggested that virtually all hirsute women may have an increase in free T, 21 there are clearly some women in whom such an abnormality cannot be detected. Furthermore, al though elevated, plasma free T does not correlate with the severity of hirsutism in women, leaving part of the puzzle unexplained.…”