Idiopathic hypereosinophilic syndrome: Magnetic resonance imaging findings in endomyocardial fibrosis

Abstract

Significant eosinophilia and even eosinophilic tissue infiltration has been associated with a variety of clinical disorders including allergic and immunodeficiency states, drug reaction, infection, parasitic infestation and malignancy. Eosinophilia without an underlying aetiology and with multi-organ dysfunction has been designated idiopathic hypereosinophilic syndrome. We report a case of endomyocardial fibrosis with MRI findings.

Acute eosinophilic endomyocarditis: early diagnosis and localisation of the lesion by cardiac magnetic resonance imaging

“…2) or fibrosis in these regions. The location of hyper-enhancement is typical, albeit less extensive, to that previously described for Löffler endocarditis [1,6,7]. LV volumes and the ejection fraction were normal based on CMR findings.…”

“…CMR performed at presentation showed diffuse subendocardial DHE in the entire ventricle with involvement of the papillary muscles. For more advanced extensive myocardial fibrosis, MRI has been reported to demonstrate generalised thickening of the ventricular wall with the ventricular cavity virtually obliterated [7] Cine MRI can reveal akinesia or hypokinesia of the involved ventricular wall and valvular regurgitation. In addition, serial MRI allows monitoring of the disease and response to therapy [6,7].…”

Cardiac magnetic resonance imaging of eosinophilic endomyocardial disease

“…MRI findings of endomyocardial fibrosis have been rarely reported in the literature [4,5]. Previously reported CMR findings of HES include increased T2 signal intensity of the endocardium, endocardial enhancement after gadolinium administration, and one report of the use of delayed enhancement viability sequences to diagnose endomyocardial fibrosis [5].…”

Cardiac Magnetic Resonance in Hypertrophic Cardiomyopathy

“…Hypereosinophilic syndrome. Hypereosinophilic syndrome presents with apical fibrosis and mural thrombus, frequently leading to apical cavity obliteration, and therefore can sometimes mimic apical HCM on TTE (42). Areas of increased subendocardial signal intensity are often observed.…”