Idiopathic peripapillary subretinal neovascular membrane in a young woman with recurrence of the lesion during pregnancy after treatment with intravitreal bevacizumab

Abstract

We report a 27-year-old woman who was diagnosed with idiopathic peripapillary subretinal neovascular membrane (PSRNVM) in her left eye with best-corrected visual acuity (BCVA) of 20/160. She had been treated by three monthly doses of intravitreal bevacizumab (1.25 mg/0.05 ml) at 4-week intervals, which showed a favorable response. The treatment led to regression of the choroidal neovascular membrane (CNVM) with complete resorption of subretinal fluid and improvement of BCVA to 20/25. Subsequently, recurrence of the CNVM was observed during pregnancy (28 months after treatment). To the best of our knowledge, this is the first report of recurrence of idiopathic PSRNVM during pregnancy.

Peripapillary Choroidal Neovascular Membrane: A Case Report

“…Moreover, it may provide CNVM images with improved occult CNVM delineation using blood or serous fluid. However, since the advent of anti-VEGF medication, the significance of ICG in assessing the clinical features of CNVM has significantly decreased [4]. The leaking pattern and the site of neovascularization can be determined with the aid of fluorescein and indocyanine green angiography.…”