Idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia should stay separate

Collard, Harold R.; King, Talmadge E.

doi:10.1183/09031936.00168607

Cited by 5 publications

(2 citation statements)

References 14 publications

(12 reference statements)

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“…Daten aus Groß-britannien lassen eine Inzidenz von 8,6 Patienten/ 100 000 Einwohner in Deutschland vermuten [1]. Die IPF gehört damit noch zu den seltenen Lungenerkrankungen und Medikamente für die IPF tragen einen "orphan drug" Status [2].…”

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Die idiopathische Lungenfibrose

Prasse

2015

Pneumologie

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Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia and a disease of the elderly. Cigarette smoking and longterm exposure to substances harming alveolar epithelial cells are risk factors for the development of IPF. There is also evidence for a genetic susceptibility. IPF is defined as the idiopathic variant of Usual Interstitial Pneumonitis (UIP). Diagnosis of IPF is complex and based on the exclusion of other diseases associated with an UIP pattern. The only cure is lung transplantation. In the last years there was a breakthrough in the treatment of IPF. With pirfenidone and nintedanib there are now two compounds approved for the treatment of IPF

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Die idiopathische Lungenfibrose

Prasse

2015

Pneumologie

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“…We recently reviewed the data of 30 patients suffering of idiopathic pulmonary fibrosis (IPF; n= 22) or idiopathic non-specific interstitial pneumonia (NSIP; n=18), according to the international consensus statement, admitted in our intensive care unit (ICU) for acute respiratory failure (ARF) between 01/01/1999 and 31/12/2009 (Table 1). We chose to associate the two patterns in the same study because IPF and NSIP closely mimic each other clinically, despite the fact that some authors believe that they should remain separate (3,4). Among 30 patients, 15 (50%) were hospitalized in ICU for acute exacerbation (AE), 9 (30%) for pulmonary infection and 6 (20%) for miscellaneous causes.…”

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confidence: 99%