Idiopathic subglottic stenosis in a nine-year-old boy: diagnosis and management

Bodart, Eddy; Remacle, Marc; Lawson, Georges; Mayné, Alain; Vandenbossche, Pierre

doi:10.1002/(sici)1099-0496(199802)25:2<136::aid-ppul12>3.0.co;2-8

Cited by 4 publications

(4 citation statements)

References 11 publications

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“…It usually presents with dyspnea, sometimes accompanied by cough and dysphonia [1,2,3,6,10,11,12,13,15,19,23]. It usually presents with dyspnea, sometimes accompanied by cough and dysphonia [1,2,3,6,10,11,12,13,15,19,23].…”

Section: Introductionmentioning

confidence: 99%

“…Many different treatment options have been advocated recently for the management of ISS, even though medical therapy frequently plays a purely palliative role and factual improvement is usually obtained only by means of surgical therapy by an endoscopic or open-neck approach [1,2,6,9,10,23]. We here present our experience in the diagnosis and treatment of 30 consecutive cases of ISS encountered in the clinical practice of an academic institution during a 17-year period.…”

Section: Introductionmentioning

confidence: 99%

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Idiopathic subglottic stenosis: management by endoscopic and open-neck surgery in a series of 30 patients

Giudice

Piazza

Foccoli

et al. 2003

Eur Arch Otorhinolaryngol

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We describe our experience in the diagnosis and treatment of idiopathic subglottic stenosis (ISS), a rare pathological entity involving the subglottic larynx and the first tracheal rings and affecting virtually only females. Its diagnosis can be made only after the exclusion of all other known causes of subglottic stenosis. In a 17-year period, between January 1986 and June 2002, 30 patients were admitted and treated for ISS at the Department of Otolaryngology and/or the Center for Respiratory Endoscopy and Laser Therapy, the University of Brescia, Italy. Clinical, endoscopic and surgical records were retrospectively analyzed with particular emphasis on treatment (endoscopic versus open-neck procedures) and follow-up. Based on our experience, we can define endoscopic treatment by carbon dioxide or Nd:YAG laser-assisted dilatation and scar tissue resection with or without airway stenting as the treatment of choice for the initial management of ISS. After repeated endoscopic failures, open-neck surgery by laryngoplasty or laryngotracheal resection and anastomosis is strongly recommended, particularly for complex lesions longer than 1 cm.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Idiopathic subglottic stenosis: management by endoscopic and open-neck surgery in a series of 30 patients

Giudice

Piazza

Foccoli

et al. 2003

Eur Arch Otorhinolaryngol

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“…Common postoperative complications apart from restenosis are local granulation, subcutaneous emphysema, wound infections, and pneumonia ( 18 , 29 , 30 ), damage to the recurrent laryngeal nerve, anastomotic dehiscence, and pneumothorax ( 31 , 73 ). More complications are expected in cases with any type of airway comorbidity ( 8 , 13 , 33 , 35 , 37 , 71 ).…”

Section: Reviewmentioning

confidence: 99%

“…Inhalative steroids are seldom used as adjunct therapy ( 2 , 5 , 8 , 33 , 79 ). There is doubt about the success of inhalative steroids in the treatment of iSGS, as this disease is regularly mistreated as asthma without success.…”

Section: Reviewmentioning

confidence: 99%

Case report: Idiopathic subglottic stenosis in a girl; successful treatment with macrolides

et al. 2022

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An 8-year-old girl presented with treatment-refractory cough and inspiratory stridor. Bronchoscopies showed progressive scarring leading to narrowing of the proximal trachea (Myer-Cotton Grade 2) and epithelial metaplasia of the tracheal and bronchial mucosa. After excluding other causes of congenital and acquired tracheal stenosis, an idiopathic subglottic tracheal stenosis (iSGS) was diagnosed. Because of the patient's young age, a judicious therapeutic approach seemed appropriate. Therapy with azithromycin, followed by roxithromycin, was started. Symptoms almost completely subsided, spirometry normalized, and endoscopic and histologic findings improved considerably. Therapy has been continued for more than 3 years with normal lung function values, and no compromise on physical activities and development. In instances of iSGS, therapy with macrolides is worth considering before more invasive procedures such as dilatation, laser, intralesional injections, or surgical resection are performed.

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