Idiopatisk intrakranial hypertensjon

Visual and quantitative analyses of fundus and optical coherent tomography (OCT) images of the optic nerve (ON) and retina were performed in Russian cosmonauts during a space flight (SF). The OCT images were used to measure the peripapillar retinal thickness, the ON head thickness, the distance between Bruch's membrane, and the degree of excavation. A visual analysis of the fundus images did not always make it possible to accurately detect optic disc edema and to classify the changes with a papilledema scale. The quantitative analysis of the OCT images showed that assessing the peripapillar retinal and ON head thicknesses at several time points is more important in the diagnosis of papilledema than measuring the distance between Bruch's membrane or the diameter and depth of the optic nerve head cup, especially at stages 0-II. The retinal thickness on opposite sides of the ON disc in in-flight OCT images was increased as compared with preflight images in all cases, suggesting ON head edema. A quantitative analysis of OCT images allows not only objective accurate diagnosis of papilledema, but also its classification by stage. An additional subclinical stage, where papilledema is diagnosed only by quantitative analysis of OCT images, was proposed to introduce in the classification.

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Spaceflight-Associated Neuro-Ocular Syndrome: Clinical Features and Classification

Макаров

Voronkov

Богомолов

et al. 2021

Hum Physiol

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Idiopatisk intrakranial hypertensjon

Abstract: Narrative oversiktsartikler basert på forfatters egen erfaring og et skjønnsmessig utvalg artikler. Klinisk oversiktIdiopatisk intrakranial hypertensjon 1895 -8

Cited by 1 publication

References 22 publications

Spaceflight-Associated Neuro-Ocular Syndrome: Clinical Features and Classification

Spaceflight-Associated Neuro-Ocular Syndrome: Clinical Features and Classification

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