IFSO Worldwide Survey 2016: Primary, Endoluminal, and Revisional Procedures

Angrisani, Luigi; Santonicola, Antonella; Iovino, Paola; Vitiello, Antonio; Higa, Kelvin; Himpens, Jacques; Buchwald, Hēnry; Scopinaro, Nicola

doi:10.1007/s11695-018-3450-2

Cited by 841 publications

(477 citation statements)

References 42 publications

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“…Most of the surgical techniques reduce the volume of the stomach, and many of them also reduce the intestinal absorptive surface area by bypassing different parts of the proximal intestine. In 2016, SG was the most performed primary surgical procedure worldwide (54%), followed by RYGBP (30%) …”

Section: Introductionmentioning

confidence: 99%

“…In 2016, SG was the most performed primary surgical procedure worldwide (54%), followed by RYGBP (30%). 10 The anatomical and physiological alterations in the gastrointestinal (GI) tract following bariatric surgery may change a wide variety of factors involved in restricting the oral bioavailability of drugs. [11][12][13][14][15] The overall process of restricting oral drug bioavailability ( F) may be divided into three main processes: the fraction of drug that is absorbed into the intestinal gut wall ( F A ), the fraction that escapes gut wall metabolism ( F G ), and the fraction that escapes hepatic metabolism ( F H ).…”

Section: Introductionmentioning

confidence: 99%

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The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review

et al. 2019

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Summary Anatomical changes in the gastrointestinal tract and subsequent weight loss may influence drug disposition and thus drug dosing following bariatric surgery. This review systematically examines the effects of bariatric surgery on drug pharmacokinetics, focusing especially on the mechanisms involved in restricting oral bioavailability. Studies with a longitudinal before‐after design investigating the pharmacokinetics of at least one drug were reviewed. The need for dose adjustment following bariatric surgery was examined, as well as the potential for extrapolation to other drugs subjected to coinciding pharmacokinetic mechanisms. A total of 22 original articles and 32 different drugs were assessed. The majority of available data is based on Roux‐en‐Y gastric bypass (RYGBP) (18 of 22 studies), and hence, the overall interpretation is more or less limited to RYGBP. In the case of the majority of studied drugs, an increased absorption rate was observed early after RYGBP. The effect on systemic exposure allows for a low degree of extrapolation, including between drugs subjected to the same major metabolic and transporter pathways. On the basis of current understanding, predicting the pharmacokinetic change for a specific drug following RYGBP is challenging. Close monitoring of each individual drug is therefore recommended in the early postsurgical phase. Future studies should focus on the long‐term effects of bariatric surgery on drug disposition, and they should also aim to disentangle the effects of the surgery itself and the subsequent weight loss.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review

et al. 2019

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“…The number of SGs performed has continually increased over the last decade and, as of recently, counts as the most common bariatric procedure worldwide. In Austria, however, SG is still outnumbered by laparoscopic Roux-en-Y gastric bypass (RYGB) [2]. …”

Section: Introductionmentioning

confidence: 99%

Quality of Life 10 Years after Sleeve Gastrectomy: A Multicenter Study

et al. 2019

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Objective: Sleeve gastrectomy (SG) has recently become the most commonly applied bariatric procedure worldwide. Substantial regaining of weight or severe reflux might compromise quality of life (QOL) after SG in the long-term follow-up. Long-term data on patients’ QOL is limited, even though the persistent improvement in QOL is one of the aims of bariatric surgery. The objective of this study was to present patients’ QOL 10 years after SG. Methods: Of 65 SG patients with a follow-up of ≥10 years after SG who were asked to fill out the Bariatric Quality of Life Index (BQL) and Short Form 36 (SF36) questionnaires, 48 (74%) completed them. This multicenter study was performed in a university hospital setting in Austria. Results: The BQL score revealed nonsignificant differences between the patients with > 50% or < 50% excess weight loss (EWL). It did show significant differences between patients with and without any symptoms of reflux. Patients with < 50% EWL scored significantly lower in 3/8 categories of SF36. Patients suffering from reflux had significantly lower scores in all categories. Conclusions: EWL and symptomatic reflux impair patients’ long-term QOL after SG.

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“…One of the recent methods, sleeve gastrectomy (SG), has shown promising results [5][6][7]. SG is therefore becoming more popular as a surgical tool against obesity both worldwide [8] and in the USA where it surpassed all other techniques in 2014 [9]. The mechanism of SG is not fully elucidated, but it involves restrictional, hormonal, and adaptational mechanisms [10].…”

Section: Introductionmentioning

confidence: 99%

Reduced Need for In-hospital Care After Sleeve Gastrectomy: a Single Center Observational Study

Kakoulidis

Arvidsson²,

Graf

et al. 2019

OBES SURG

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Setting Private clinic, Stockholm, and nation-wide in-hospital care, Sweden. Objectives The use of sleeve gastrectomy (SG) for treatment of morbid obesity has increased worldwide, but information about long-term outcome is still limited. Our objective was to evaluate the need for additional in-hospital care after SG for obesity (body mass index [BMI] > 30) in 862 patients, all operated at a single center. Methods Two national registries, the Inpatient Registry and the Death Registry, were used to collect long-term data on inhospital care, grouped by the International Statistical Classification of Diseases and Related Health Problems (ICD-10) and mortality, respectively. Results In-hospital care for SG-operated females was decreased for four groups of obesity-related ICD-10 diagnoses: endocrine and metabolic diseases and circulatory, digestive, and genitourinary diseases, as well as injuries and poisoning (p < 0.001 for all). However, female SG patients still required in-hospital care above the national level for women of corresponding ages. Conclusions Although a significant reduction in in-hospital care was observed, SG patients did not reach national levels.Open Access This article is distributed under the terms of the Creative Comm ons Attribution 4.0 International License (http:// creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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IFSO Worldwide Survey 2016: Primary, Endoluminal, and Revisional Procedures

Abstract: In 2016, there was an increase in the total number both of surgical and endoluminal bariatric/metabolic procedures. Revisional procedures represent about 7% of the total bariatric interventions. SG remains the most performed surgical procedure in the world.

Cited by 841 publications

References 42 publications

The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review

The influence of bariatric surgery on oral drug bioavailability in patients with obesity: A systematic review

Quality of Life 10 Years after Sleeve Gastrectomy: A Multicenter Study

Reduced Need for In-hospital Care After Sleeve Gastrectomy: a Single Center Observational Study

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