IgA-Pemphigus

Abstract

IgA pemphigus is a rare intraepidermal autoimmune disease characterized by the presence of intercellular IgA deposits, intraepidermal acantholysis with infiltration of neutrophils, and circulating IgA autoantibodies against keratinocyte cell surface components. We report for the first time about a patient with IgA pemphigus who was successfully treated with mycophenolate mofetil.

Discrepancies among clinical, histological and immunological findings in IgA pemphigus: a case report and literature survey

“…However, various types of treatment have also been reported in IgA pemphigus like retinoids [9], systemic corticosteroids at moderate doses alone or in combination with immunosuppressive agents [6]. Rarely, azithromycin [10] or mycophenolate mofetil [11] may be used in intractable cases.…”