IgE sensitization profiles toward green and gold kiwifruits differ among patients allergic to kiwifruit from 3 European countries

Bublin, Merima; Mari, Adriano; Ebner, Christof; Knulst, André C.; Scheiner, Otto; Hoffmann‐Sommergruber, Karin; Breiteneder, Heimo; Radauer, Christian

doi:10.1016/j.jaci.2004.07.016

Cited by 104 publications

(106 citation statements)

References 33 publications

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“…20,21) Several reports have been published on kiwi fruit in relation to allergy. [22][23][24] In addition, a report has been recently published on 8-OHdG, 25) but not on HEL after the intake of kiwi fruit. Nowadays, metabolic syndrome is attracting a lot of attention.…”

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confidence: 99%

Anti-oxidant Effects of Kiwi Fruit in Vitro and in Vivo

Iwasawa

Morita

Yui

et al. 2011

Biological & Pharmaceutical Bulletin

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We previously reported that kiwi fruit is rich in polyphenols and has immunostimulatory activity. Polyphenols are widely known for having anti-oxidant effects. We also revealed potential anti-oxidant effects of kiwi fruit in vivo by oral administration to mice. Here, we compared the anti-oxidant effects of kiwi fruit with those of other fruits in vitro. Then, we examined the inhibitory effects of kiwi fruit on oxidation in the human body. There are two varieties of kiwi fruit, green kiwi and gold kiwi. We also examined variation between these varieties. Comparison of the anti-oxidant effects in vitro demonstrated that kiwi fruit had stronger anti-oxidant effects than orange and grapefruit, which are rich in vitamin C; gold kiwi had the strongest anti-oxidant effects. Kiwi fruit inhibited oxidation of biological substances in the human body. In particular, kiwi fruit may inhibit early lipid oxidation. In this study, kiwi fruit had strong anti-oxidant effects and may prevent the development and deterioration of diseases caused by oxidative stress.

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confidence: 99%

Anti-oxidant Effects of Kiwi Fruit in Vitro and in Vivo

Iwasawa

Morita

Yui

et al. 2011

Biological & Pharmaceutical Bulletin

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“…Mal d 2 from apple (Malus domestica) was the first allergen described as a TLP (28). Following the identification of Mal d 2, several fruit allergens, including Pru av 2 from cherry (Prunus avium), Act c 2 and Act d 2 from kiwi (Actinidia chinensis and A. deliciosa, respectively), Cap a 1 from bell pepper (Capsicum annuum) and thaumatin from grape (Vitis vinifera), were reported as allergens belonging to the PR5 family (19,(29)(30)(31)(32). Recently, PR-5 allergens from pollen have been identified as Jun a 3 from mountain cedar (J. ashei), Jun v 3 from eastern red cedar (J. virginiana) and Cup a 3 from C. arizonica (20,22,33).…”

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confidence: 99%

Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen

Fujimura

Futamura

Midoro-Horiuti

et al. 2007

Allergy

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Background-Japanese cedar (Cryptomeria japonica) pollinosis is the most prevalent allergy in Japan. Recently, the Japanese cedar pollen allergen Cry j 3 was cloned as a homologue of Jun a 3, which is a major allergen from mountain cedar (Juniperus ashei) pollen. However, native Cry j 3 has not been isolated and there are no reports on its allergenic activity. The aims of this study were to isolate native Cry j 3 and assess its immunoglobulin E (IgE)-binding capacity in patients with Japanese cedar pollinosis.

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“…These TLPs can be found in pollen and different foods such as NP24 from tomato (Solanum lycopersicon) (Sharma et al 2011), Cup a 3 from cypress (Cupressus arizonica) (Breiteneder 2004), Act d 2 kiwi fruit (Actinidia deliciosa) (Bublin et al 2004) and Mal d 2 from apple (Malus domestica) (Hsieh et al 1995).…”

Section: Clinical Manifestationsmentioning

confidence: 99%

Cannabis Allergy: What do We Know Anno 2015

Decuyper

Ryckebosch

Gasse

et al. 2015

Arch. Immunol. Ther. Exp.

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For about a decade, IgE-mediated cannabis (marihuana) allergy seems to be on the rise. Both active and passive exposure to cannabis allergens may lead to a cannabis sensitization and/or allergy. The clinical manifestations of a cannabis allergy can vary from mild to lifethreatening reactions, often depending on the route of exposure. In addition, sensitization to cannabis allergens can trigger various secondary cross-allergies, mostly for plant-derived food. This clinical entity, which we have designated as the ''cannabis-fruit/vegetable syndrome'' might also imply cross-reactivity with tobacco, latex and plant-food derived alcoholic beverages. These secondary cross-allergies are mainly described in Europe and appear to result from cross-reactivity between non-specific lipid transfer proteins or thaumatin-like proteins present in Cannabis sativa and their homologues that are ubiquitously distributed throughout plant kingdom. At present, diagnosis of cannabis-related allergies rests upon a thorough history completed with skin testing using native extracts from buds and leaves. However, quantification of specific IgE antibodies and basophil activation tests can also be helpful to establish correct diagnosis. In the absence of a cure, treatment comprises absolute avoidance measures including a stop of any further cannabis (ab)use.

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IgE sensitization profiles toward green and gold kiwifruits differ among patients allergic to kiwifruit from 3 European countries

Cited by 104 publications

References 33 publications

Anti-oxidant Effects of Kiwi Fruit in Vitro and in Vivo

Anti-oxidant Effects of Kiwi Fruit in Vitro and in Vivo

Isolation and characterization of native Cry j 3 from Japanese cedar (Cryptomeria japonica) pollen

Cannabis Allergy: What do We Know Anno 2015

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