IgG4-related disease presented with a neck nodule; a case report

Abstract

Introduction and importance: Immunoglobulin G4 (IgG4)-related disease is an infrequent systemic condition that affects males more than females. Fatigue, arthralgia, salivary and lacrimal gland enlargement, symptoms of pancreatitis, tubulointerstitial nephritis, and retroperitoneal fibrosis are the frequent manifestations. The spectrum of IgG4-related thyroid disease includes Hashimoto thyroiditis, Graves’ disease, and Riedel thyroiditis. Case presentation: We presented a 49‐year‐old male presented with progressive painless swallowing of the neck for a year without any accompanying symptoms. Conclusion: Expanding goiter is common, but its severity leads to the rare diagnosis of IgG4-related thyroiditis.