IgM/IgG antibody changes in asymptomatic and discharged patients with reoccurring positive nucleic acid test (RP) of Novel Coronavirus Disease 2019 (COVID-19)

Abstract

Background It has been reported that antibody testing could improve diagnostic efficiency of COVID-19 infection. However the IgM/IgG changes in asymptomatic and discharged patients with reoccurring positive RT-PCR test (RP) remained elusive. Methods 111 patients with positive RT-PCR test and 40 suspected patients were enrolled. We evaluated the diagnostic performance of IgM/ IgG antibodies. Furthermore, the IgM/IgG levels with the disease progress in asymptomatic and RP patients were analyzed. Results Of the 111 RT-PCR positive cases, 17 (15.5%), 42(38.2%), 22 (20%) and 30(27.0%) were

Method Validation Study for SARS-CoV-2 Viral RNA Detection in Cervical, Rectal, Amniotic Fluid, Placental, Umbilical Cord Blood, and Breastmilk Specimens in a Cohort of Unvaccinated Women in Manila, Philippines

“…21 Furthermore, SARS-CoV-2 detection in stool specimens has already been confirmed by numerous studies that investigated other routes of viral transmission. 4,[22][23][24] These findings suggest a higher likelihood of SARS-CoV-2 detection in rectal swabs, and anorectum can be a potential route for mother-to-child transmission during normal delivery.…”