BackgroundPsoriasis is a chronic, inflammatory, relapsing skin disease that has a
psychosocial impact on the patients' life.ObjectiveThis study aimed to investigate psychopathology in patients with psoriasis
based on a valid psychometric instrument, as well as on the relationship
between psychopathology and alexithymia.Methods108 patients with psoriasis were included in the study. Psychopathology was
evaluated with the Symptom Checklist-90-Revised (SCL-90-R) and alexithymia
with the Toronto Alexithymia Scale (TAS-20). Disease severity was clinically
assessed using the Psoriasis Area and Severity Index.ResultsAs regards the psychopathological dimensions, female patients presented with
statistically significant higher somatization, depression, anxiety, phobic
anxiety, and psychoticism than males. Patients with alexithymia presented
with statistically significant higher somatization, interpersonal
sensitivity, anxiety, and phobic anxiety than non-alexithymic patients.
Alexithymia positively correlated with somatization (r = 0.26, p < 0.01),
interpersonal sensitivity (r = 0.24, p < 0.05), depression (r = 0.27, p
< 0.01), anxiety (r = 0.26, p < 0.01), and phobic anxiety (r = 0.26, p
< 0.01). In addition, alexithymia also contributed to the prediction of
these conditions.Study LimitationsA larger study sample could yield safer generalized results. Nevertheless, to
the best of our knowledge, this was the first study to investigate various
psychopathological dimensions in patients with psoriasis.ConclusionsOur study results indicate that alexithymia and female sex were associated
with several psychopathological dimensions in patients with psoriasis. It
may be suggested that alexithymia constitutes an important factor in the
development of mental disorders among patients with psoriasis.