Illness Perception in Inflammatory Bowel Disease Patients is Different Between Patients With Active Disease or in Remission: A Prospective Cohort Study

Vegni, Elena; Gilardi, Daniela; Bonovas, Stefanos; Corrò, Bianca E; Menichetti, Julia; Leone, Daniela; Allocca, Mariangela; Furfaro, Federica; Danese, Silvio; Fiorino, Gionata

doi:10.1093/ecco-jcc/jjy183

Cited by 48 publications

(31 citation statements)

References 29 publications

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“…The illness perception refers to the mental image one has about the disease, in terms of causes, symptoms, consequences and personal control. In IBD, previous studies have shown that the activity of the disease has an impact on the perception of the disease (28). This study shows that the presence of certain symptoms is also relevant for how patients perceive their disease.…”

Section: Discussionsupporting

confidence: 50%

Psychosocial profile of the patients with inflammatory bowel disease

et al. 2020

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Inflammatory bowel disease (IBD) is a chronic, disabling entity of unknown aetiology, with negative impact on the patient's life, including psychological patterns. This study assessed multiple psychosocial factors (satisfaction with life, coping mechanisms, emotional profile, mental recognition of the disease and cognition schemes related to patients' demographic characteristics, clinical picture, form and duration of the disease, therapeutic plans) in IBD patients vs. a healthy group. This non-interventional study comprised 60 participants who attended for medical advice/check-up as an ambulatory visit or during hospitalization. The patients completed questionnaires after receiving explanations from the psychologist. Statistical analyses (Kolmogorov-Smirnov test, Independent-Samples t-test, One-Way ANOVA and Post Hoc Multiple Comparisons) were conducted using IMB for the Social Sciences (SPSS), version 20 (P≤0.05). IBD patients (G1) are more hostile when compared to the healthy group (G2). Those who experience abdominal pain are more likely to use active coping mechanisms and those who experience fatigue are more likely to use acceptance, emotional venting, behavioural disengagement and mental disengagement. G1 have higher levels of others-downing vs. G2. Regarding negative emotions, IBD patients generally experience more negative emotions compared to healthy participants (who have higher levels of life satisfaction). Regarding the perception of illness, there are no differences between patients in terms of illness coherence, personal or treatment control, consequences, timeline, or emotional representations. Results indicate that psychological factors and different characteristics of IBD patients play a relevant role in the way these patients deal with their disease.

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Section: Discussionsupporting

confidence: 50%

Psychosocial profile of the patients with inflammatory bowel disease

et al. 2020

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“…Fatigue is a common symptom of patients with chronic inflammatory diseases such as chronic hepatitis C, 2 rheumatologic diseases, 3 cancer, 4 systemic lupus erythematosus, 5 and IBD 6 . In addition to depression, anxiety 7 and impaired quality of life, 8 fatigue and lack of energy are the most prevalent psychosocial symptoms in IBD 9 . Fatigue, in turn, affects quality of life, social functioning 10 and absence from work, 11 thus conveying a large part of the public health and economic impact of IBD.…”

Section: Introductionmentioning

confidence: 99%

Fatigue in inflammatory bowel disease and its impact on daily activities

Schreiner

Rossel

Biedermann

et al. 2020

Aliment Pharmacol Ther

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SummaryBackgroundFatigue is a common symptom of chronic inflammation, including inflammatory bowel disease (IBD), resulting in significant impairment in quality of life.AimsTo identify the prevalence of fatigue in a large IBD cohort compared to the general population, address risk factors, and evaluate its impact on daily life.MethodsWe evaluated 1208 IBD patients from the Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS) and 414 healthy controls. Significant fatigue was defined as a visual analogue scale (VAS‐F, range 0‐10) score ≥ 4. Secondary endpoints were severity of fatigue and its impact on daily activities with the Fatigue Severity Scale (FSS), with a score ≥ 4 indicative of fatigue. Demographic, IBD‐related and psychiatric symptoms were assessed with a multivariate analysis of variance (MANOVA) model optimised for prediction of VAS‐F (primary outcome) and FSS scores.ResultsOverall, 672 IBD patients (55.6%) reported significant fatigue compared to 145 (35%) controls (OR 2.71; 95% CI 2.08‐3.54; P < 0.001). In IBD, fatigue also significantly affected daily activities (FSS ≥ 4; 405 (33.5%) IBD patients vs 81 (19.6%) controls, P < 0.001). In the MANOVA model, fatigue levels were associated with female gender (coefficient 0.839; 0.556 ‐ 1.123; P < 0.001), younger age at diagnosis (−0.031 per year; −0.042– −0.019; P < 0.001), shorter disease duration (−0.036 per year; −0.050– −0.022; P < 0.001), nocturnal diarrhoea (0.718; 0.295‐1.141; P = 0.001), low educational level (P = 0.034) and symptoms of depression and anxiety.ConclusionsFatigue is both more frequent and more severe in patients with IBD than in the general population.

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“…In the case of chronic diseases like IBD, it is preferable to talk about health-related quality of life (HRQoL), which can be defined as the value assigned to the lifespan, taking into account the influence of limitations, changes in functional capacities, alterations of subjective perceptions, and impediments to social opportunities that an illness can determine [6]. Particularly during the phases of active disease, IBD patients report a strong impairment of HRQoL, dealing with anxiety, depression, sleep disturbance, and fatigue [7]. Although there was a strong confirmation that HRQoL is poorer during active disease, this condition frequently persists during the quiescent phases of the disease [8].…”

Section: Introductionmentioning

confidence: 99%

The Reality of Patient-Reported Outcomes of Health-Related Quality of Life in an Italian Cohort of Patients with Inflammatory Bowel Disease: Results from a Cross-Sectional Study

Larussa

Abenavoli

Boccuto

et al. 2020

JCM

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Inflammatory bowel disease (IBD) has a negative impact on patients’ physical and psychological well-being, social performance, and working capacity, thereby worsening their health-related quality of life (HRQoL). Clinicians should take care of the patients’ global health, including the psychological, social, and emotional spheres. We aimed to investigate the reality of patient-reported outcomes of HRQoL in a series of IBD patients. Consecutive Crohn´s disease (CD) and ulcerative colitis (UC) patients in clinical remission were recruited. The survey consisted of the Short Inflammatory Bowel Disease Questionnaire (S-IBDQ), the Hospital Anxiety and Depression Scale (HADS), the Brief Illness Perception Questionnaire (B-IPQ), and a questionnaire dealing with impact of IBD on patients’ lives. Demographic and clinical characteristics were recorded. Of 202 participants (29% CD and 71% UC; 54% male; median age 48 years; mean disease duration 14 ± 11 years), 52% had poor HRQoL, 45% anxiety/depression, and 35% sleep disturbance and a high perception of disease (mean score 42.8 ± 14.3). In the multivariate analysis, a low HRQoL was rather associated with UC than CD (p = 0.037), IBD surgery (p = 0.010), disease duration (p = 0.01), sleep disturbance (p = 0.014), anxiety/depression (p = 0.042), and high illness perception (p = 0.006). IBD affected working performance and social activities in 62% and 74% of patients, respectively. Satisfaction regarding quality of care, biologics, and surgery approach were claimed in 73%, 69%, and 76% of patients, respectively. Although 84% of patients trusted their gastroenterologist, only 66% of them discussed IBD impact on HRQoL during visit. In a series of IBD patients in remission, the low HRQoL was significantly associated with surgery, disease duration, sleep disturbance, anxiety/depression, and high illness perception. Even though patients were satisfied with the quality of their care, it appears that clinicians should pay more attention to patients’ emotional status.

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Illness Perception in Inflammatory Bowel Disease Patients is Different Between Patients With Active Disease or in Remission: A Prospective Cohort Study

Cited by 48 publications

References 29 publications

Psychosocial profile of the patients with inflammatory bowel disease

Psychosocial profile of the patients with inflammatory bowel disease

Fatigue in inflammatory bowel disease and its impact on daily activities

The Reality of Patient-Reported Outcomes of Health-Related Quality of Life in an Italian Cohort of Patients with Inflammatory Bowel Disease: Results from a Cross-Sectional Study

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