Image‐based computational fluid dynamics for estimating pressure drop and fractional flow reserve across iliac artery stenosis: A comparison with in‐vivo measurements

Barrientos, Pauline Hall; Matthews, James L.; Radjenovic, Aleksandra; Mark, Patrick B.; Roditi, Giles; Paul, Manosh C.

doi:10.1002/cnm.3437

Cited by 9 publications

(3 citation statements)

References 38 publications

(51 reference statements)

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“…This image-based numerical modeling has been applauded as a precursor for achieving real-time computer-driven clinical medicine. Skopalik et al [35] presented a robust numerical assessment to predict pressure drop using image-based data in a scenario of iliac-type arterial stenosis. However, there are certain issues limiting the utilization of image-computing in a numerical scheme in the cases of arterial stenosis [36].…”

Section: Introductionmentioning

confidence: 99%

Numerical Analysis of Au/Hybird Nanofluid Flowing Through an Asymmetry-Type Stenotic Rotator-Cuff Balloon under the Influence of Magnetic Field

Ige¹,

Oyelami²,

Etokowoh³

et al. 2023

IJDNE

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Rotator-cuff tear and vascular-related stenosis are common diseases in the elder persons. A balloon-like rotator-cuff is proscribed as the usual clinical intervention. Recently, computational schemes are being sought to enhance clinical outcomes in vascular-related repairs. This paper presents a numerical treatment of asymmetrically-shaped goldembedded nanoparticle in stenotized conduit under the influence of magnetic field. We described the dynamics of fluid and particle transport under externally imposed field effect using established mathematical formulations. Thereafter, a robust numerical scheme built around spectra-relaxation scheme to implement the solution over conformation in the Au-blood stream under magnetic field imposition.

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Section: Introductionmentioning

confidence: 99%

Numerical Analysis of Au/Hybird Nanofluid Flowing Through an Asymmetry-Type Stenotic Rotator-Cuff Balloon under the Influence of Magnetic Field

Ige¹,

Oyelami²,

Etokowoh³

et al. 2023

IJDNE

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“…In the presence of this pathological condition, three scenarios can occur, namely, amputation, revascularization, or the death of the patient as a result of cardiovascular events [23]. Given the impact of this disease on human health, some investigations have been conducted [18,[24][25][26][27][28], but further hemodynamic studies in these stenotic arteries are needed.…”

Section: Introductionmentioning

confidence: 99%

Numerical Study of the Unsteady Flow in Simplified and Realistic Iliac Bifurcation Models

Carvalho

Carneiro

Ferreira

et al. 2021

Fluids

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Cardiovascular diseases are a major cause of death and disability worldwide and they are commonly associated with the occurrence of atherosclerotic plaque deposition in the vessel walls, a process denoted as atherosclerosis. This is a chronic and progressive inflammatory disease of large-/medium-sized blood vessels that affects blood flow profiles, with the abdominal aorta and its branches being one of the locations prone to the development of this pathology, due to their curvatures and bifurcations. In this regard, the effect of flow patterns was studied and compared for both a simplified three-dimensional model of aorta bifurcation on the iliac arteries and a realistic model of iliac bifurcation, which was constructed from a computational tomography medical image. The flow patterns were analyzed in terms of velocity and wall shear stress distribution, but a special focus was given to the size and location of the recirculation zone. The simulations were performed using the Computational Fluid Dynamics software, FLUENT, taking into account the cardiac cycle profile at the infrarenal aorta. The shear stress and the velocity distribution observed for both models indicated that higher shear stress occurred along the flow divider wall (inner wall) and low shear stress occurred along the outer walls. In addition, the results demonstrated that the wall shear stress profiles were deeply affected by the transient profile of the cardiac cycle, with the deceleration phase being the most critical phase to the occurrence of backflow.

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“…FFR was initially described by Pijls et al, who used pressure estimations in the absence of stenosis [13]. FFR has been shown to be reliable in identifying stenosis severity [14].…”

Section: Introductionmentioning

confidence: 99%

Evaluating the effect of non-Newtonian turbulent blood models within a double-stenosed artery

Al-Azawy

2021

ejuow

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This article describes the numerical investigation of blood rheology within an artery that includes two narrowing areas via Computational Fluid Dynamics (CFD). Elliptic blending Reynolds stress model and two models of viscosity have been used in this investigation utilizing STAR-CCM+ 2021.2.1. The test model includes two elliptical stenosis with a 2mm distance between them, and the area of stenosis is 75%. Results of normalized axial velocity, turbulent kinetic energy (TKE) and turbulent viscosity ratio (TVR) were evaluated before, through and after the stenosis in order to predict and avoid the real problems that occur from changing the area of the artery. Furthermore, Fractional flow reserve (FFR) was employed to assess the level of risk of stenosis through the artery, which depends on pressure measurements. Corresponding to the author's observation, it was found that the recirculation regions in the area between the stenosis are larger than the area after the stenosis. Moreover, the results of TKE and TVR are almost identical through and downstream of the stenosis, whereas the TKE is slightly higher with the Carreau model than with the Newtonian flow at the upstream and through the first stenosis.

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Image‐based computational fluid dynamics for estimating pressure drop and fractional flow reserve across iliac artery stenosis: A comparison with in‐vivo measurements

Cited by 9 publications

References 38 publications

Numerical Analysis of Au/Hybird Nanofluid Flowing Through an Asymmetry-Type Stenotic Rotator-Cuff Balloon under the Influence of Magnetic Field

Numerical Analysis of Au/Hybird Nanofluid Flowing Through an Asymmetry-Type Stenotic Rotator-Cuff Balloon under the Influence of Magnetic Field

Numerical Study of the Unsteady Flow in Simplified and Realistic Iliac Bifurcation Models

Evaluating the effect of non-Newtonian turbulent blood models within a double-stenosed artery

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