Image Gallery: Acute primary cutaneous nocardiosis due to <i>Nocardia brasiliensis</i>

Zhuang, Kaiwen; Tang, Juan; Ran, Yu Ping

doi:10.1111/bjd.15394

Cited by 4 publications

(2 citation statements)

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“…Therefore, it is generally considered an opportunistic infection. Its clinical variability includes lymphocutaneous syndrome,[ 1 ] superficial skin infection[ 2 ] (pustule, pyoderma, abscess, ulcer, granuloma, or cellulitis), chronic conditions of hyperkeratotic plaques, tumor-like masses, and mycetoma[ 3 ] along with systemic nocardiosis cutaneous involvement. In some instances, the infection may also be subclinical and resolve spontaneously.…”

Section: Discussionmentioning

confidence: 99%

Erythematous Lesions with Erosions and Swelling on the Right Forearm

Xiao

Pradhan

Zhuang

et al. 2022

Indian Journal of Dermatology

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Section: Discussionmentioning

confidence: 99%

Erythematous Lesions with Erosions and Swelling on the Right Forearm

Xiao

Pradhan

Zhuang

et al. 2022

Indian Journal of Dermatology

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“…The course of treatment varies from 7 days to 2 years according to the severity of the infection, clinical symptoms and immunosuppressive conditions [20,21]. Traditional intensive antibiotic therapy has been reported to increase survival rates, but the overall prognosis of nocardiosis patients remains relatively poor; additionally, coadministration of interferon gamma significantly improves the condition of those with serious infections [22].…”

Section: Discussionmentioning

confidence: 99%

Erythema Nodosum following Nocardia Infection: A Case Report

Teng

et al. 2022

Medicina

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Cutaneous nocardiosis is a rare bacterial infection that can result in various dermatologic manifestations such as actinomycetoma, lymphocutaneous infection, superficial skin infection, and secondary infection due to hematogenous dissemination. We report on a Chinese patient with erythema nodosum-like exanthema, possibly secondary to nocardiosis. Our diagnosis for this patient was based on the clinical presentation, histopathological evidence, and microbiological findings. Given the protean manifestation of Nocardia, persistent reports on new presentations of the disease are important for early identification and treatment.

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Isolated Nocardiosis, an Unrecognized Primary Immunodeficiency?

Martı́nez-Barricarte

2020

Front. Immunol.

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Nocardiosis is an infectious disease caused by the gram-positive bacterium Nocardia spp. Although it is commonly accepted that exposure to Nocardia is almost universal, only a small fraction of exposed individuals develop the disease, while the vast majority remain healthy. Nocardiosis has been described as an "opportunistic" disease of immunocompromised patients, suggesting that exposure to the pathogen is necessary, but a host predisposition is also required. Interestingly, increasing numbers of nocardiosis cases in individuals without any detected risk factors, i.e., without overt immunodeficiency, are being reported. Furthermore, a growing body of evidence have shown that selective susceptibility to a specific pathogen can be caused by a primary immunodeficiency (PID). This raises the question of whether an undiagnosed PID may cause nocardiosis affecting otherwise healthy individuals. This review summarizes the specific clinical and microbiological characteristics of patients with isolated nocardiosis published during the past 30 years. Furthermore, it gives an overview of the known human immune mechanisms to fend off Nocardia spp. obtained from the study of PIDs and patients under immunomodulatory therapies.

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Image Gallery: Acute primary cutaneous nocardiosis due to Nocardia brasiliensis

Cited by 4 publications

References 1 publication

Erythematous Lesions with Erosions and Swelling on the Right Forearm

Erythematous Lesions with Erosions and Swelling on the Right Forearm

Erythema Nodosum following Nocardia Infection: A Case Report

Isolated Nocardiosis, an Unrecognized Primary Immunodeficiency?

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