2011
DOI: 10.1159/000322485
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Image-Guided, Adaptive Radiotherapy of Prostate Cancer: Toward New Standards of Radiotherapy Practice

Abstract: The development and acceptance of new image-guided radiotherapy (IGRT) technologies have often been initiated with the treatment of prostate cancer. Imaging and tracking of the prostate during a treatment course has yielded a great deal of information about the motion and deformation of the gland during radiotherapy, and has led the way toward the development of more accurate treatment methods including dose-guided and adaptive strategies. Now, there is long-term experience with the use of fiducials and electr… Show more

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Cited by 24 publications
(11 citation statements)
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“…The studies of Ghilezan [39] and Nederveen [40] have shown an influence of the delivery time on intrafraction organ motion: the longer the fractional treatment lasts the higher is the risk of anatomic deviation. Kupelian [41] argued with this potentially mismatch for daily image guidance and adaptive radiotherapy. In contrast actually there exists no defined standard recommendation for online correction in daily practice when using a VMAT technique for treating prostate cancer.…”
Section: Discussionmentioning
confidence: 99%
“…The studies of Ghilezan [39] and Nederveen [40] have shown an influence of the delivery time on intrafraction organ motion: the longer the fractional treatment lasts the higher is the risk of anatomic deviation. Kupelian [41] argued with this potentially mismatch for daily image guidance and adaptive radiotherapy. In contrast actually there exists no defined standard recommendation for online correction in daily practice when using a VMAT technique for treating prostate cancer.…”
Section: Discussionmentioning
confidence: 99%
“…Deformable image registration and adaptive planning strategies are required to address this problem, a detailed discussion of which is beyond the scope of this review, but an overview of these topics is given by Maintz and Viergever, 53 Kashani et al 54 and Kupelian and Meyer. 55 Pouliot et al 29 measured IMDs of 3 gold implanted markers in 11 patients using orthogonal MV image pairs. They observed a time trend in three patients where the distance between all three markers decreased over the course of radiotherapy, suggesting overall shrinkage of the prostate.…”
Section: Prostate Fiducial Marker Migrationmentioning
confidence: 99%
“…Image-guided radiotherapy (IGRT) is commonly used to reduce setup errors in patient positioning and in the inter-fraction organ motion [8, 9]. Typically, the correction parameter involves moving the treatment table to re-position the shifted target point to the isocenter of the treatment device.…”
Section: Introductionmentioning
confidence: 99%