Image-guided intraoperative radiation therapy: current developments and future perspectives

Pascau, Javier

doi:10.1586/17434440.2014.929494

Cited by 3 publications

(3 citation statements)

References 14 publications

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“…With its origins in clinical use dating back to the 1960s, IOERT has been demonstrated to be feasible and effective in local control of disease in breast, pancreas, soft tissue sarcomas, head and neck, uterine, and colorectal cancers ( 8 , 9 ). Structural limitations of the applicator tube have restricted use to cavities with clear line-of-sight parameters, although the recently described potential to link IOERT delivery devices to electromagnetic surgical navigation systems could afford access to previously unattainable targets ( 10 , 11 ). Despite decades of use in non-cranial sites, only a single institutional experience has been published describing intracranial use in high-grade glioma ( 12 ).…”

Section: Iort Nomenclaturementioning

confidence: 99%

Intraoperative Radiotherapy in Brain Malignancies: Indications and Outcomes in Primary and Metastatic Brain Tumors

Cifarelli

Jacobson

2021

Front. Oncol.

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Despite the continued controversy over defining an optimal delivery mechanism, the critical role of adjuvant radiation in the management of surgically resected primary and metastatic brain tumors remains one of the universally accepted standards in neuro-oncology. Local disease control still ranks as a significant predictor of survival in both high-grade glioma and treated intracranial metastases with radiation treatment being essential in maximizing tumor control. As with the emergence and eventual acceptance of cranial stereotactic radiosurgery (SRS) following an era dominated by traditional radiotherapy, evidence to support the use of intraoperative radiotherapy (IORT) in brain tumors requiring surgical intervention continues to accumulate. While the clinical trial strategies in treating glioblastoma with IORT involve delivery of a boost of cavitary radiation prior to the planned standard external beam radiation, the use of IORT in metastatic disease offers the potential for dose escalation to the level needed for definitive adjuvant radiation, eliminating the need for additional episodes of care while providing local control equal or superior to that achieved with SRS in a single fraction. In this review, we explore the contemporary clinical data on IORT in the treatment of brain tumors along with a discussion of the unique dosimetric and radiobiological factors inherent in IORT that could account for favorable outcome data beyond those seen in other techniques.

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Section: Iort Nomenclaturementioning

confidence: 99%

Intraoperative Radiotherapy in Brain Malignancies: Indications and Outcomes in Primary and Metastatic Brain Tumors

Cifarelli

Jacobson

2021

Front. Oncol.

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“…Due to its effectiveness IORT has been applied for different kinds of cancers like pancreatic cancer, rectal cancer, early breast cancer, retroperitoneal sarcoma, and selected gynecologic and genitourinary cancers (Pascau 2014).…”

Section: _________________________________________________________________________mentioning

confidence: 99%

“…Though the small sample size of these studies is not enough for a concrete conclusion, adjuvant IOERT helped to improve local control (Pinheiro et al 2003) with no major intraoperative or postoperative complications. The common complications after IOERT are wound complications, fistulae, osteoradionecrosis and neuropathy (Abe et al 1991, Roukos 2009, Pascau 2014, Wilson et al 2019, Dagenais et al 2020. Another complication that might occur after IOERT is carotid artery blow which can _________________________________________________________________________ be avoided by shielding or moving out the major vessels and nerves from the treatment field (Pinheiro et al 2003).…”

Section: Head and Neck Cancermentioning

confidence: 99%

2D-3D Image Registration for Image Guided Intraoperative Radiotherapy

Goswami¹

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A 3D Image Registration Method for Laparoscopic Liver Surgery Navigation

Wang

2022

Electronics

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At present, laparoscopic augmented reality (AR) navigation has been applied to minimally invasive abdominal surgery, which can help doctors to see the location of blood vessels and tumors in organs, so as to perform precise surgery operations. Image registration is the process of optimally mapping one or more images to the target image, and it is also the core of laparoscopic AR navigation. The key is how to shorten the registration time and optimize the registration accuracy. We have studied the three-dimensional (3D) image registration technology in laparoscopic liver surgery navigation and proposed a new registration method combining rough registration and fine registration. First, the adaptive fireworks algorithm (AFWA) is applied to rough registration, and then the optimized iterative closest point (ICP) algorithm is applied to fine registration. We proposed a method that is validated by the computed tomography (CT) dataset 3D-IRCADb-01. Experimental results show that our method is superior to other registration methods based on stochastic optimization algorithms in terms of registration time and accuracy.

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Image-guided intraoperative radiation therapy: current developments and future perspectives

Cited by 3 publications

References 14 publications

Intraoperative Radiotherapy in Brain Malignancies: Indications and Outcomes in Primary and Metastatic Brain Tumors

Intraoperative Radiotherapy in Brain Malignancies: Indications and Outcomes in Primary and Metastatic Brain Tumors

2D-3D Image Registration for Image Guided Intraoperative Radiotherapy

A 3D Image Registration Method for Laparoscopic Liver Surgery Navigation

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