Compressive sensing is a powerful tool to efficiently acquire and reconstruct an image even in diffuse optical tomography (DOT) applications. In this work, a time-resolved DOT system based on structured light illumination, compressive detection, and multiple view acquisition has been proposed and experimentally validated on a biological tissue-mimicking phantom. The experimental scheme is based on two digital micromirror devices for illumination and detection modulation, in combination with a time-resolved single element detector. We fully validated the method and demonstrated both the imaging and tomographic capabilities of the system, providing state-of-the-art reconstruction quality. In the last decade, the possibility to quantitatively reconstruct absorbing, scattering, and fluorescent inclusions within in vivo organisms attracted a great deal of interest for diagnostic purposes (e.g., tumor detection) [1], functional studies (e.g., brain oximetry) [2], and molecular imaging on small animals (e.g., pharmacological research) [3]. The general measurement scheme consists of illuminating a sample and detecting the diffused light exiting it. Then, by solving the inverse problem, based on a model of photon propagation through the biological tissue, the optical parameters in each point of the sample can be reconstructed quantitatively. These modalities are usually referred to as diffuse optical tomography (DOT) or fluorescence molecular tomography (FMT) when, respectively, the absorption/ scattering or fluorescence properties are reconstructed. The performance of DOT/FMT is mainly characterized by its capability to resolve the position and shape of inhomogeneities inside the tissue, and, consequently, improve the quantification capability of their optical parameters. Previous studies have demonstrated the importance of a dense source/detector [4] and a multiple view measurement scheme [5,6] in order to increase the tomographic spatial resolution. Moreover, further data, such as spectral and temporal information, are crucial [7,8]. Temporal information provides three main advantages: (i) better disentanglement of absorption/scattering properties, (ii) temporal encoding of photon depth, and (iii) fluorescence lifetime quantification in the case of FMT. Spectral information (i.e., different excitation/detection wavelength) allows one to discriminate among tissue chromophores. Hence, DOT/FMT turns out to be a highly multidimensional problem with the drawback of a huge data set being generated. This represents a practical limitation of these techniques because of the extremely long acquisition and computational times, which are not typically compatible with clinical and preclinical needs. Hence, a reduction of the acquired data set by preserving the spatial resolution, or, more generally, the data set information content, is highly desirable.Following this concept, different studies have recently exploited the fact that a highly scattering medium (such as biological tissue) behaves as a low-pass filter in the spatial do...