Imagerie fonctionnelle cérébrale appliquée à l’analyse des phénomènes douloureux

Peyron, R.; Faillenot, Isabelle

doi:10.1051/medsci/201127182

Cited by 13 publications

(6 citation statements)

References 51 publications

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“…The neuro-imaging work during the last three decades have shown the SII and insular areas to be key pain integration areas [25]. In fact, a recent combined MEG-fMRI study by Mochizuki et al confirmed that itch signals are mainly located in the secondary somatosensory cortex (SII)/insula, which were also activated in the fMRI experiment by the itch stimuli[6], [26].…”

Section: Discussionmentioning

confidence: 98%

Analysis for Distinctive Activation Patterns of Pain and Itchy in the Human Brain Cortex Measured Using Near Infrared Spectroscopy (NIRS)

et al. 2013

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Pain and itch are closely related sensations, yet qualitatively quite distinct. Despite recent advances in brain imaging techniques, identifying the differences between pain and itch signals in the brain cortex is difficult due to continuous temporal and spatial changes in the signals. The high spatial resolution of positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) has substantially advanced research of pain and itch, but these are uncomfortable because of expensiveness, importability and the limited operation in the shielded room. Here, we used near infrared spectroscopy (NIRS), which has more conventional usability. NIRS can be used to visualize dynamic changes in oxygenated hemoglobin and deoxyhemoglobin concentrations in the capillary networks near activated neural circuits in real-time as well as fMRI. We observed distinct activation patterns in the frontal cortex for acute pain and histamine-induced itch. The prefrontal cortex exhibited a pain-related and itch-related activation pattern of blood flow in each subject. Although it looked as though that activation pattern for pain and itching was different in each subject, further cross correlation analysis of NIRS signals between each channels showed an overall agreement with regard to prefrontal area involvement. As a result, pain-related and itch-related blood flow responses (delayed responses in prefrontal area) were found to be clearly different between pain (τ = +18.7 sec) and itch (τ = +0.63 sec) stimulation. This is the first pilot study to demonstrate the temporal and spatial separation of a pain-induced blood flow and an itch-induced blood flow in human cortex during information processing.

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Section: Discussionmentioning

confidence: 98%

Analysis for Distinctive Activation Patterns of Pain and Itchy in the Human Brain Cortex Measured Using Near Infrared Spectroscopy (NIRS)

et al. 2013

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“…An update published by Peyron and Faillenot [17] demonstrated that the rostral cingulate cortex as well as medial prefrontal areas are associated with activation in pain relief. They postulate that activation in these areas may correlate with the magnitude of pain relief, activation of the periaqueductal gray and possible release of endogenous opioids [17]. …”

Section: Discussionmentioning

confidence: 99%

“…Bogod et al [28] targeted the subgenual cingulate gyrus in 4 patients with treatment-resistant depression and were able to demonstrate improved cognitive abilities using serial neuropsychological evaluations. Taken together, this body of literature leads to the conclusion that anterior cingulate cortical cells play an important role in mediating many of the higher cortical responses to pain [17,26]. …”

Section: Discussionmentioning

confidence: 99%

Further Evidence for a Pain Pathway Involving the Cingulate Gyrus: A Case of Chronic Cluster Headache Cured by Glioblastoma

Robin¹,

Pabaney²,

Mitsias

et al. 2015

Stereotact Funct Neurosurg

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The authors report a case of a 49-year-old man with long-standing, chronic cluster headache (CH) refractory to medical therapy and occipital nerve stimulation that resolved a few weeks prior to the diagnosis of glioblastoma involving primarily the right cingulate gyrus. An attempt to explore the underlying role of the cingulate cortex in pain modulation by appraising the current literature is presented. This report suggests that the cingulate gyri could be a potential target for neuromodulation in patients with medically refractory chronic CH.

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“…Avant le début du traitement, chaque patient a bénéficié d'une imagerie par résonnance magnétique fonctionnelle (IRMf) afin d'enregistrer l'activité cérébrale au repos [11] (➜). À la fin de la période de traitement, les patients dont les douleurs ont diminué d'au moins 20 % ont été qualifiés de répondeurs au placebo ; les autres de non-répondeurs ( Figure 1A).…”

Section: Nouvelleunclassified

Prédire la réponse placebo grâce à l’imagerie par résonance magnétique fonctionnelle

Tétreault

Apkarian

2017

Med Sci (Paris)

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Imagerie fonctionnelle cérébrale appliquée à l’analyse des phénomènes douloureux

Cited by 13 publications

References 51 publications

Analysis for Distinctive Activation Patterns of Pain and Itchy in the Human Brain Cortex Measured Using Near Infrared Spectroscopy (NIRS)

Analysis for Distinctive Activation Patterns of Pain and Itchy in the Human Brain Cortex Measured Using Near Infrared Spectroscopy (NIRS)

Further Evidence for a Pain Pathway Involving the Cingulate Gyrus: A Case of Chronic Cluster Headache Cured by Glioblastoma

Prédire la réponse placebo grâce à l’imagerie par résonance magnétique fonctionnelle

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