Four experiments investigated the conditions contributing to sensorimotor alignment effects (i.e., the advantage for spatial judgments from imagined perspectives aligned with the body). Through virtual reality technology, participants learned object locations around a room (learning room) and made spatial judgments from imagined perspectives aligned or misaligned with their actual facing direction. Sensorimotor alignment effects were found when testing occurred in the learning room but not after walking 3 m into a neighboring (novel) room. Sensorimotor alignment effects returned after returning to the learning room or after providing participants with egocentric imagery instructions in the novel room. Additionally, visual and spatial similarities between the test and learning environments were independently sufficient to cause sensorimotor alignment effects. Memory alignment effects, independent from sensorimotor alignment effects, occurred in all testing conditions. Results are interpreted in the context of two-system spatial memory theories positing separate representations to account for sensorimotor and memory alignment effects.Keywords: spatial memory, spatial updating, sensorimotor interference, perspective taking, alignment effectAn everyday task such as providing a friend with directions to one's home can entail imagining the friend's perspective and telling him or her whether to turn left or right at intersections. The ease with which a person can reason from a perspective and/or location other than one's own has been shown to depend on at least three factors: the perspectives one experienced when learning the imagined space (Diwadkar & McNamara, 1997;Shelton & McNamara, 1997), the structure of the space itself (McNamara, Rump & Werner, 2003;Mou & McNamara, 2002;Shelton & McNamara, 2001;Werner & Schmidt, 1999), and the position and orientation of the person's body during recall (May, 2004;Mou, McNamara, Valiquette, & Rump, 2004;Presson & Montello, 1994;Rieser, 1989). Reasoning about space is often easier from perspectives aligned rather than misaligned with salient reference frames (e.g., environmental reference frames or the body's reference frame). This empirical result is termed an alignment effect. Herein, we distinguish between two kinds of alignment effects. We refer to the advantage of responding from imagined perspectives that are aligned rather than misaligned with the body during retrieval as a sensorimotor alignment effect. As an example, the reader is invited to close his or her eyes and imagine the immediate surrounds from his or her current location and orientation in the environment. The reader is then asked to try to imagine how things would look if he or she were to rotate in place 180°. The increased difficulty after imagined rotation is an example of a sensorimotor alignment effect. Additionally, we refer to the advantage of reasoning from a perspective aligned rather than misaligned with the reference frames used to encode an environment in long-term memory as a memory alignment effe...