2011
DOI: 10.1016/j.bbrc.2010.12.043
|View full text |Cite
|
Sign up to set email alerts
|

Imaging and measuring the rituximab-induced changes of mechanical properties in B-lymphoma cells using atomic force microscopy

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

2
38
0
5

Year Published

2012
2012
2018
2018

Publication Types

Select...
5
3

Relationship

3
5

Authors

Journals

citations
Cited by 49 publications
(45 citation statements)
references
References 42 publications
2
38
0
5
Order By: Relevance
“…Atomic force microscopy (AFM) [11] provides nanoscale topographic resolution and can dynamically observe changes in mechanical properties of single cells, such as those following stimulation by drugs [12,13]. These aspects have made AFM become an important tool for the measurement of mechanical properties of biomaterials [14,15], and those of cells [16,17].…”
mentioning
confidence: 99%
“…Atomic force microscopy (AFM) [11] provides nanoscale topographic resolution and can dynamically observe changes in mechanical properties of single cells, such as those following stimulation by drugs [12,13]. These aspects have made AFM become an important tool for the measurement of mechanical properties of biomaterials [14,15], and those of cells [16,17].…”
mentioning
confidence: 99%
“…For each cell measured, 20 force curves were obtained using the same loading rate for each one. For computing the Young's modulus, the Hertz model was used (Touhami et al 2003;Li et al 2011):…”
Section: Mechanical Properties Measurementmentioning
confidence: 99%
“…Mammalian suspended cells are soft and have large size, causing the porous polymer membrane method or pure electrostatic adsorption unsuitable. In order to observe the changes of nanostructures on living lymphoma cells (a type of human suspended cell) during the rituximab's PCD mechanism, we have developed an immobilization method combining micro-fabricated pillar's mechanical trapping and poly-L-lysine electrostatic adsorption [22,23], as shown in Fig. 2.…”
Section: Pcd Mechanismmentioning
confidence: 99%
“…However, due to the limit of 200-nm resolution, traditional optical microscopy cannot reveal the dynamic developments of MACs on the cell Fig. 2 Changes of cellular nanostructures and mechanical properties during the PCD mechanism of rituximab revealed by AFM [22,23]. a SEM image of the micro-fabricated pillars.…”
Section: Cdc Mechanismmentioning
confidence: 99%
See 1 more Smart Citation