Imaging and surgical outcomes of spinal tumors in 18 dogs and one cat

Beşaltı, Ömer; Çalışkan, Murat; Can, Pınar; Vural, Sevil Atalay; Algın, Oktay; Ahlat, Ozan

doi:10.4142/jvs.2016.17.2.225

Cited by 45 publications

(79 citation statements)

References 26 publications

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“…Surgical gross total tumour removal of vertebral tumours improves the quality of life (Besalti et al 2016). No surgical complications were observed in our case.…”

Section: Discussionsupporting

confidence: 48%

Meningioma in cervical spinal cord segment 6 of a dog – a case report

et al. 2018

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Meningiomas in dogs occur more commonly in the brain than in the cranial spinal cord. Intramedullary spinal cord tumours in dogs are described infrequently and present a diagnostic and therapeutic challenge. A nine-year-old Beagle dog was referred because of tetraparesis of a 20-day duration. The neurological signs were suggestive of a selective lesion involving the cervical spinal cord. Sagittal T2-weighted magnetic resonance imaging of the cervical vertebral column revealed a ventral, well-circumscribed mass within the vertebral canal at the level of cervical segment 6 (C6). A primary neoplasia was considered as probable differential diagnosis. The mass was removed by cervical laminectomy, durotomy and gentle dissections. On the basis of histological and immunohistochemical findings, a diagnosis of transitional meningioma (grade I) was made. Treatment of the meningioma with surgery resulted in a complete recovery, the dog was able to walk 21 days after surgery and had normal walk two months after presentation. Clinicopathologic and treatment data of cranial intraspinal meningiomas have been reported sporadically, but a segment 6 location was not thoroughly described before.

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“…Surgical gross total tumour removal of vertebral tumours improves the quality of life (Besalti et al 2016). No surgical complications were observed in our case.…”

Section: Discussionsupporting

confidence: 48%

Meningioma in cervical spinal cord segment 6 of a dog – a case report

et al. 2018

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“…These studies have shown extremely wide variability in survival time, from several days to several years after surgery. Adjunctive therapies were used variably among the dogs in these studies and therefore direct comparison of outcomes and determination of the most effective treatment modalities is challenging . The largest of these case series was reported almost 20 years ago and included 10 dogs with primary vertebral OSA, 4 dogs with metastatic vertebral OSA and 6 dogs with vertebral fibrosarcoma, with a reported survival time ranging from 15‐600 days.…”

Section: Introductionmentioning

confidence: 99%

Surgical decompression, with or without adjunctive therapy, for palliative treatment of primary vertebral osteosarcoma in dogs

Dixon

Chen

Rossmeisl

et al. 2019

Vet Comparative Oncology

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Vertebral osteosarcoma (OSA) is the most common primary vertebral tumor in dogs, however studies examining the survival time after surgical decompression of these tumors are limited. There is also limited information regarding the benefit of adjunctive treatments such as radiation therapy or chemotherapy in these patients. The goal of this study was to determine survival time of dogs with primary vertebral OSA after palliative decompressive surgery alone and combined with radiation therapy and/or chemotherapy. Records from 22 client-owned dogs diagnosed with primary vertebral OSA and treated with decompressive surgery were collected retrospectively from eight referral institutions. Survival time was assessed for dogs treated with surgery alone as well as dogs who received adjunctive radiation therapy and/or chemotherapy. Median survival time in the 12 dogs treated with surgery alone was 42 days (range: 3-1333 days). The three dogs treated with surgery and chemotherapy had a median survival time of 82 days (range: 56-305 days). Only one dog was treated with surgery and radiation therapy; this dog survived 101 days. Six dogs were treated with surgery, radiation therapy and chemotherapy; these dogs had a median survival time of 261 days (range: 223-653 days). Cause of death in all cases that survived the initial postoperative period was euthanasia secondary to confirmed or suspected tumor regrowth. The results of this study suggest that definitive radiation therapy, possibly combined with concurrent chemotherapy, significantly improves survival in dogs treated with palliative decompressive surgery for vertebral OSA and should be the treatment of choice in selected cases.

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“…Kippenes and colleagues previously reported MRI findings in dogs with vertebral tumors but only two of the dogs were diagnosed with vertebral plasmacytomas . Magnetic resonance imaging offers several advantages over radiography as a diagnostic imaging modality for investigation of spinal disease, and is considered part of the “gold standard” imaging for human multiple myeloma patients . Veterinary literature describing MRI findings in dogs diagnosed with multiple myeloma is currently lacking.…”

Section: Introductionmentioning

confidence: 99%

“…6 Magnetic resonance imaging offers several advantages over radiography as a diagnostic imaging modality for investigation of spinal disease, and is considered part of the "gold standard" imaging for human multiple myeloma patients. [7][8][9][10] Veterinary literature describing MRI findings in dogs diagnosed with multiple myeloma is currently lacking.…”

mentioning

confidence: 99%

Neurological signs and MRI findings in 12 dogs with multiple myeloma

Wyatt

Risio

Driver³

et al. 2019

Vet Radiology Ultrasound

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Vertebral lesions and associated neurological signs occur in dogs with multiple myeloma, however, veterinary literature describing MRI findings is currently lacking. The objective of this multicenter, retrospective, case series study was to describe neurological signs and MRI findings in a group of dogs that presented for spinal pain or other neurological deficits and had multiple myeloma. Electronic records of four veterinary referral hospitals were reviewed. Dogs were included if they had a pathologically confirmed diagnosis of multiple myeloma, had presented for spinal pain or other neurological signs, and had undergone MRI of the vertebral column. The MRI studies were evaluated and the anatomical location of lesion(s), signal intensity, presence of extra‐dural material, degree of spinal cord compression, extent of vertebral lesions, and contrast enhancement were recorded. Twelve dogs met inclusion criteria. Most dogs (n = 8) had a chronic progressive history, with varying degrees of proprioceptive ataxia and paresis (n = 11), and spinal pain was a feature in all dogs. The MRI findings were variable but more consistent features included the presence of multiple expansile vertebral lesions without extension beyond the outer cortical limits of affected vertebrae, and associated extradural material causing spinal cord compression. The majority of lesions were hyper‐ to isointense on T2 (n = 12) and T1‐weighted (n = 8) sequences, with variable but homogeneous contrast‐enhancement (n = 12). These described MRI characteristics of multiple myeloma may be used to aid early identification and guide subsequent confirmatory diagnostic steps, to ultimately improve therapeutic approach and long‐term outcome.

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Imaging and surgical outcomes of spinal tumors in 18 dogs and one cat

Cited by 45 publications

References 26 publications

Meningioma in cervical spinal cord segment 6 of a dog – a case report

Meningioma in cervical spinal cord segment 6 of a dog – a case report

Surgical decompression, with or without adjunctive therapy, for palliative treatment of primary vertebral osteosarcoma in dogs

Neurological signs and MRI findings in 12 dogs with multiple myeloma

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