Imaging Diagnosis-FDG-Pet/Ct of a Canine Splenic Plasma Cell Tumor

Abstract

An 8-year-old Shih Tzu developed abdominal pain and hyperglobulinemia. A round splenic mass was noted radiographically and sonographically. The patient was evaluated by fluorodeoxyglucose positron emission tomography coupled with computed tomography (FDG-PET/CT). There was no evidence of metastasis or bone marrow involvement on PET/CT images. The standardized uptake value (SUV) of the splenic mass was increased over the reference range (SUV ¼ 4.83). The patient was diagnosed as splenic extramedullary plasmacytoma through immunohistopathologic study. After the splenectomy, the globulin level normalized and the patient is alive without complications. r

Imaging in Oncology

“…[104][105][106][107] Its utility for cancer staging of canine mast cell tumor and lymphoma has already been demonstrated. [109][110][111][112] Normal gray matter of the brain can confound interpretation of intracranial tumor images because of its high glucose utilization normally. The uptake of FDG in normal tissues must be understood relative to veterinary species to avoid false-positive diagnoses because some normal tissues are also highly metabolic.…”

Invited Review‐off‐site Pet Imaging Programs: Challenges and Opportunities

“…In our experience, most cats and dogs can be effectively imaged with an injected dose of 2–5 mCi of 18 FDG and thus the purchase of a single dose of 18 FDG could be split among two patients, taking into account the timing of the scans and the 110 min half‐life of the tracer. Although a review of the current literature is beyond the scope of this paper, the re‐ader should refer to the recently published literature to familiarize him/her selves with the normal pattern of uptake of 18 FDG in various species, and on the use of 18 FDG in clinical patients . Dedicated software, variable depending on the scanner used, is required for image reconstruction and interpretation, including the creation of fused images and quantitative analysis by determination of standardized uptake values (SUV).…”

18F-FDG and 11C-MET Positron Emission Tomography Findings of Cutaneous Mast Cell Tumor in a Dog

“…PET has been increasingly used in veterinary oncology [1,2,6,[11][12][13]. However, there have been no prior clinical reports describing the 11 C-MET-PET features of spontaneously occurring cutaneous MCTs of the dog.…”