Imaging Diagnosis of Transient Ischemic Attack in Clinic and Traditional Chinese Medicine

Yao, Qigu; Zhang, Lincheng; Zhou, Jing; Li, Min; Jing, Weifeng; Li, Xiaohong; Han, Jin Soo; Zhang, Yuyan

doi:10.1155/2019/5094842

Cited by 5 publications

(3 citation statements)

References 68 publications

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“…In this study, we utilized whole-brain perfusion pseudo-color maps and whole-brain vascular maps obtained through WB-CTP were used to evaluate TIA patients comprehensively and rapidly ( 21 ). Our findings revealed a correlation between the ABCD3 score, degree of intracranial vascular stenosis, and the perfusion parameters in the abnormal brain tissue perfusion areas in TIA patients.…”

Section: Discussionmentioning

confidence: 99%

Predictive value of whole-brain CT perfusion combined with ABCD3 score for short-term secondary cerebral infarction after TIA

Liu,

Chen,

2023

Front. Neurol.

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ObjectiveTo investigate the predictive value of Whole Brain CT Perfusion (WB-CTP) combined with the ABCD3 score in patients with transient ischemic attack (TIA).MethodsA total of 336 TIA patients with TIA underwent WB-CTP and ABCD3 score assessment within 48 h of admission. Spearman correlation test was performed to analyze the relationship between the degree of vascular stenosis, relative perfusion values, and ABCD3 score. Logistic regression analysis was used to identify independent risk factors for secondary cerebral infarction. Receiver operating characteristic (ROC) curves were generated to evaluate the predictive value of relative cerebral blood flow (rCBF), degree of vascular stenosis, ABCD3 score, and the WB-CTP-ABCD3 combined model for secondary cerebral infarction after TIA. Calibration curves and H-L tests were used to evaluate the predictive efficacy of the model.ResultsAmong the 336 TIA patients, 143 showed abnormal perfusion areas and 146 had responsible vessel stenosis. The degree of vascular stenosis, relative time-to-maximum (rTmax), and relative mean transit time (rMTT) were positively correlated with the ABCD3 score, while rCBF and relative cerebral blood volume (rCBV) were negatively correlated with the ABCD3 score. ROC curve analysis identified a cutoff value of 0.8205 for rCBF, with a sensitivity of 84.10% and specificity of 58.10% for distinguishing the cerebral infarction group from the non-cerebral infarction group. Furthermore, rCBF ≤ 0.8205, degree of vascular stenosis, and ABCD3 score > 6 were identified as independent risk factors for secondary cerebral infarction in TIA patients within 90 days in TIA patients. The AUC of the WB-CTP-ABCD3 combined model for predicting secondary cerebral infarction within 90 days was 0.836. The model risk was assessed by plotting calibration curves. The value of p for the H-L goodness of fit test was 0.366 (p > 0.05), which indicated that the difference between the obtained model and the perfect model were statistically insignificant.ConclusionThe combined model of WB-CTP-ABCD3 shows promise as a valuable method for predicting secondary cerebral infarction within 90 days following TIA.

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Section: Discussionmentioning

confidence: 99%

Predictive value of whole-brain CT perfusion combined with ABCD3 score for short-term secondary cerebral infarction after TIA

Liu,

Chen,

2023

Front. Neurol.

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“…Clopidogrel [15] is the most widely used drug with significant short-term efficacy and good safety and does not increase the occurrence of hemorrhagic stroke and other adverse reactions. According to traditional Chinese medicine [16], cerebral ischemia can be classified into the category of "blood stasis syndrome," and the pathogenic mechanism is blood stasis block and qi and blood obstruction. erefore, TIA is treated by supplementing qi and promoting blood circulation and clearing collaterals and meridians.…”

Section: Discussionmentioning

confidence: 99%

Clinical Study of Clopidogrel Combined with Huoxue Tongluo Prescription in Improving Transient Ischemic Attack and the Effect on MMP-9, Hcy, and CRP

Chen²,

et al. 2022

Journal of Healthcare Engineering

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Background. This study aimed to explore the clinical study of clopidogrel combined with Huoxue Tongluo prescription in improving transient ischemic attack (TIA) and the effect on MMP-9, Hcy, and CRP. Methods. A total of 84 patients with TIA admitted to our hospital from December 2019 to February 2021 were selected. The patients were divided into the control group (42 cases: not treated with Huoxue Tongluo prescription) and study group (42 cases: treatment with Huoxue Tongluo prescription). The clinical efficacy, adverse reactions, the levels of blood pressure and lipid, blood rheology and cerebral hemodynamics, neurological function-related indicators, MMP-9, Hcy, and CRP of the two groups were compared. Results. The total effective rate in the study group was higher than the control group. Compared with before treatment, the levels of SBP and DBP in both groups decreased memorably after treatment, and those in the study group decreased more particularly than the control group. The levels of LDL, HDL, TC, and TG in the study group were significantly better than those in the control group. The plasma viscosity, whole blood high shear viscosity, whole blood low shear viscosity, and hematocrit of patients in the study group were lower than those in the control group, and the maximum blood flow velocity, minimum blood flow velocity, average blood flow velocity, and average blood flow were higher than those in the control group. The levels of NSE, MBP, and S100β in the study group were more memorably lower than those in the control group. After treatment, the levels of MMP-9, Hcy, and CRP in the study group were significantly lower than those in the control group. There was no obvious difference in the incidence of adverse reactions between the study group and control group. Conclusion. Clopidogrel combined with Huoxue Tongluo prescription can significantly improve the therapeutic effect and reduce the levels of MMP-9, Hcy, and CRP in patients with TIA.

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“…Medical imaging techniques provide valuable supplemental support for TCM practitioners in the diagnosis of transient ischemic attacks. Medical imaging in TCM focuses primarily on identifying categories, assessing the effectiveness of TCM treatments, and integrating TCM with Western medicine [31] . These developments demonstrate that TCM is progressive in nature, satisfies modern diagnostic and therapeutic demands, and has yielded favorable outcomes in clinical studies and applications [32][33] .…”

Section: Synergizing Diagnostic Approaches: Integrating Tcm and Weste...mentioning

confidence: 99%

Intelligent Acupuncture: Data-driven Revolution of Traditional Chinese Medicine

Bao,

Ding,

Zhang

et al. 2023

Acupuncture and Herbal Medicine

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Acupuncture, a form of traditional Chinese medicine with a history of 2000 years in China, has gained wider acceptance worldwide as a complementary therapy. Studies have examined its effectiveness in various health conditions and it is commonly used alongside conventional medical treatments. With the development of artificial intelligence (AI) technology, new possibilities for improving the efficacy and precision of acupuncture have emerged. This study explored the combination of traditional acupuncture and AI technology from three perspectives: acupuncture diagnosis, prescription, and treatment evaluation. The study aimed to provide cutting-edge direction and theoretical assistance for the development of an acupuncture robot.

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Imaging Diagnosis of Transient Ischemic Attack in Clinic and Traditional Chinese Medicine

Cited by 5 publications

References 68 publications

Predictive value of whole-brain CT perfusion combined with ABCD3 score for short-term secondary cerebral infarction after TIA

Predictive value of whole-brain CT perfusion combined with ABCD3 score for short-term secondary cerebral infarction after TIA

Clinical Study of Clopidogrel Combined with Huoxue Tongluo Prescription in Improving Transient Ischemic Attack and the Effect on MMP-9, Hcy, and CRP

Intelligent Acupuncture: Data-driven Revolution of Traditional Chinese Medicine

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