Imaging features of the less common pancreatic masses

Hammond, Nancy; Miller, Frank H.; Day, Kevin; Nikolaidis, Paul

doi:10.1007/s00261-012-9922-2

Cited by 22 publications

(9 citation statements)

References 34 publications

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“…It is difficult to diagnose a pancreatic tumor without a history of such diseases due to the lack of typical features of pancreatic plasmacytoma on CT, magnetic resonance imaging (MRI), and other examinations. 1 There were only 7 case reports, including our present case, that did not have a history of multiple myeloma or related disease (Table 1 ). 2 – 7 The present patient was oldest.…”

Section: Discussionmentioning

confidence: 86%

“…However in the present case, multiphase contrast-enhanced CT revealed solid masses with homogenous enhancement in the arterial phase. Although Hammond et al 1 reviewed the several case reports and proposed that the most typical finding of pancreatic plasmacytoma on CT might be the presence of a focal multilobulated mass with homogeneous contrast enhancement, the features of pancreatic plasmacytoma on multiphase contrast-enhancement CT have not been established. Further analysis with the accumulation of cases of pancreatic plasmacytoma will clarify the characteristic findings of pancreatic plasmacytoma on CT, MRI, and other examinations.…”

Section: Discussionmentioning

confidence: 99%

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The Detection of Pancreatic and Retroperitoneal Plasmacytoma Helped to Diagnose Multiple Myeloma

Utsumi

Sasajima²,

Goto³

et al. 2015

Medicine

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Multiple myeloma is characterized by the neoplastic proliferation of a single clone of plasma cells producing a monoclonal protein. However, the involvement of pancreas is a rare event. We herein report a rare case of pancreatic plasmacytoma, which was detected before the diagnosis of multiple myeloma.An 83-year-old male was referred to our hospital for further evaluation of obstructive jaundice and a pancreatic mass. A contrast-enhanced computed tomography (CT) scan revealed solid masses with homogenous enhancement in the pancreatic head and retroperitoneum. The histological findings of the retroperitoneal mass obtained by CT-guided biopsy showed multiple sheets of atypical plasma cells, which were positively immunostained for CD79a, CD138, and the κ light chain. Serum immunoelectrophoresis detected M-component of immunoglobulin A-κ, and the histological findings of the bone marrow revealed an abnormally increased number of atypical plasma cells with irregular nuclei and cytoplasmic vacuolation. The patient was therefore diagnosed to have multiple myeloma involving the pancreas and retroperitoneum. Although chemotherapy was performed, the patient died 6 months after the diagnosis.The pancreatic plasmacytoma was detected before the multiple myeloma in the present case. It is difficult to diagnose a pancreatic plasmacytoma without a history of multiple myeloma and related disease.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

The Detection of Pancreatic and Retroperitoneal Plasmacytoma Helped to Diagnose Multiple Myeloma

Utsumi

Sasajima²,

Goto³

et al. 2015

Medicine

View full text Add to dashboard Cite

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“…On imaging both masses were hypo-enhancing with the larger lesion having evidence of necrosis. These features have been previously documented in ACC, with the presence of necrosis usually seen in larger lesions while smaller lesions are usually more solid in appearance (18,19). Primary ACCs most frequently metastasizes to the liver, therefore it is important to clearly establish that the liver lesions are not representative of metastatic disease from a pancreas ACC (1).…”

Section: Discussionmentioning

confidence: 89%

Case report: primary acinar cell carcinoma of the liver treated with multimodality therapy

Jordan

Basturk

Shia

et al. 2017

J. Gastrointest. Oncol.

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We describe a case of primary acinar cell carcinoma (ACC) originating in the liver in a 54-year-old female, diagnosed following persistent abnormal elevated liver function. Imaging revealed two masses, one dominant lesion in the right hepatic lobe and another in segment IVA. A right hepatectomy was performed to remove the larger lesion, while the mass in segment IVA was unresectable due to its proximity to the left hepatic vein. Immunohistochemical staining showed positivity for trypsin and chymotrypsin. Postoperatively the patient underwent hepatic arterial embolization of the other unresectable lesion followed by FOLFOX chemotherapy. At 20 months from diagnosis the patient is currently under observation with a decreasing necrotic mass and no other disease evident. Based on histology, immunohistochemistry and radiological findings a diagnosis of primary ACC of the liver was made. Genomic assessment of somatic mutations within the patient's tumor was also performed through next generation sequencing and findings were consistent with an acinar malignancy. This case highlights a rare tumor subtype treated with a combination of therapeutic modalities through a multidisciplinary approach.

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“…In 2006, Hois et al 7 analyzed 6000 CT scans and identified pancreatic lipomas in 5 of them (0.083%). In 2013, Hammond et al 8 also described a variety of uncommon benign and malignant pancreatic neoplasms. Recently, in 2014, Gossner et al 9 retrospectively reviewed 100 abdominal CT scans, of which 6 had pancreatic lipomas (6%).…”

Section: Discussionmentioning

confidence: 99%

Pancreatic lipoma: a pancreatic incidentaloma; diagnosis with ultrasound, computed tomography and magnetic resonance imaging

et al. 2016

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Pancreatic lipomas are rare. We present a case of incidentally discovered pancreatic lipoma in a 45-year-old female suffering from metastatic ovarian carcinoma who was referred to radiology for follow-up imaging. Fat-containing tumours originating from the pancreas are very rare. Most lipomasshow characteristic features on imaging that allow their differentiation. In most cases, accurate diagnosis is attained without any histopathological confirmation. We present the imaging features of pancreatic lipoma on ultrasound, CT scan and MRI, the differential diagnosis and a brief review of the literature.

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Imaging features of the less common pancreatic masses

Cited by 22 publications

References 34 publications

The Detection of Pancreatic and Retroperitoneal Plasmacytoma Helped to Diagnose Multiple Myeloma

The Detection of Pancreatic and Retroperitoneal Plasmacytoma Helped to Diagnose Multiple Myeloma

Case report: primary acinar cell carcinoma of the liver treated with multimodality therapy

Pancreatic lipoma: a pancreatic incidentaloma; diagnosis with ultrasound, computed tomography and magnetic resonance imaging

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