Imaging follow-up study of acute rhinosinusitis

Abstract

4 Laryngoscope, 126:1965-1970, 2016.

Longitudinal analysis of inflammatory biomarkers during acute rhinosinusitis

“…The facts that the local and systemic inflammatory responses were stronger in bacterial ARS than in nonbacterial ARS, and that these reactions were strongest at the beginning of respiratory symptoms, indicates that bacterial ARS starts to develop during an early phase of symptoms. This is in agreement with our earlier finding that there is a gradually increasing discrepancy in CBCT and symptom scores between bacterial and nonbacterial ARS that begins at the start of the symptoms . Furthermore, we have shown earlier that the presence of pathogenic bacteria in the nasal middle meatus (coinfection) at the beginning of viral ARS modifies the symptoms and is one factor that may lead to the finding of the same bacteria in the maxillary sinus .…”

“…This is in agreement with our earlier finding that there is a gradually increasing discrepancy in CBCT and symptom scores between bacterial and nonbacterial ARS that begins at the start of the symptoms. 21 Furthermore, we have shown earlier that the presence of pathogenic bacteria in the nasal middle meatus (coinfection) at the beginning of viral ARS modifies the symptoms and is one factor that may lead to the finding of the same bacteria in the maxillary sinus. 9 However, here the middle meatal NTHi was not associated with raised CRP or decreased nNO.…”

“…We have used this same study population to study the microbiology, clinical diagnostics, and imaging findings of ARS. Briefly, the patients were recruited and examined at the health center of the Kajaani Garrison, Finland.…”

“…A follow‐up visit was scheduled for the workday closest to the 10th day of symptoms. The recorded symptoms, imaging examinations, and microbiologic specimen and analyses have been described earlier in detail . What follows is a brief description of these data.…”

“…The recorded symptoms, imaging examinations, and microbiologic specimen and analyses have been described earlier in detail. 9,20,21 What follows is a brief description of these data.…”