Imaging in Colorectal Cancer

Sethi, Rishi; Lee, Stephen H.

doi:10.1007/978-0-85729-889-8_10

Cited by 5 publications

(7 citation statements)

References 27 publications

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“…The accuracy of MRI for T staging of rectal cancer ranged from 67% to 83%, 11–14 which mainly depended on the difficulty in differentiating between T1 and T2 tumors as well as the desmoplastic response of some tumors that might lead T2 tumors to be misdiagnosed as T3 tumors. 15…”

Section: Discussionmentioning

confidence: 99%

Assessment of T and N staging with MRI₃T in lower and middle rectal cancer and impact on clinical strategy

Zhang

Qin

et al. 2020

J Int Med Res

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Background To determine the diagnostic accuracy of preoperative T/N stage using MRI in lower and middle rectal cancer patients and the impacts on clinical decision-making. Patients and methods There were 354 patients recruited from May 2017 to February 2019. MRI was performed within 2 weeks before surgery. Histopathologic results were evaluated for the postoperative T/N stage and MRI diagnostic accuracy was assessed based on the postoperative histopathologic results. Accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and Kappa values were used to evaluate MRI diagnostic accuracy and analysis consistency compared with postoperative histopathologic staging. Results Overall MRI diagnostic accuracy was 78.2% and 56.8% for T1–4 and N0–2 staging. The Kappa values were 0.625 and 0.323 for T1–4 and N0–2 staging, respectively. After combination, MRI diagnostic accuracy was 85% and 69.5% for T and N staging. The Kappa values were 0.693 and 0.4 for T and N staging. The diagnostic accuracy of MRI for treatment decision-making was 79.1%. Conclusion MRI enables a highly accurate preoperative assessment of T stage but only a fairly accurate preoperative assessment of the N stage for rectal cancer with surgery. The diagnostic accuracy of MRI for treatment decision-making is promising.

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Section: Discussionmentioning

confidence: 99%

Assessment of T and N staging with MRI₃T in lower and middle rectal cancer and impact on clinical strategy

Zhang

Qin

et al. 2020

J Int Med Res

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“…The accuracy of MRI for the T staging of rectal cancer ranges from 67% to 83%, 11–14 which mainly depends on the difficulty in differentiating between T1 and T2 tumors as well as the desmoplastic response of some tumors that might lead T2 tumors to be misdiagnosed as T3 tumors 15 …”

Section: Discussionmentioning

confidence: 99%

Value of 3Tesla MRI in the preoperative staging of mid‐low rectal cancer and its impact on clinical strategies

Zhang

et al. 2020

Asia-Pac J Clncl Oncology

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Background: To determine the diagnostic accuracy of preoperative T/N stage with magnetic resonance imaging (MRI) in lower and middle rectal cancer patients and the impacts on clinical decision-making. Patients and methods: A total of 211 patients were recruited from October 2015 to March 2017 in this retrospective study. High-resolution MRI was performed within 2 weeks before surgery. Histopathologic results were evaluated for the postoperative T/N stage and the diagnostic accuracy of MRI was assessed according to the postoperative histopathologic results. The accuracy, sensitivity, specificity, positive predictive value and negative predictive value were evaluated for T/N staging and κ values were used to evaluate MRI consistent analysis compared with postoperative histopathologic staging. Results: The overall MRI diagnostic accuracy was 79.62% for T1-4 staging and 54.50% for N0-2 staging. The κ values were 0.619 and 0.255 for T1-4 and N0-2 staging, respectively. The diagnostic accuracy of MRI for treatment decision-making was 80.57%. Conclusion: MRI allows a highly accurate preoperative assessment of T stage but only a fairly accurate preoperative assessment of N stage for rectal cancer. The diagnostic accuracy of MRI for treatment decision-making is promising, but additional studies are needed to validate these findings in a larger sample size from multiple centers.

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“…These results are due, in part, to the experience of the examining physician and, on the other hand, to the difficulty of differentiating in some cases a stage T1 tumor from a stage T2 tumor. In some cases, the desmoplastic reaction of the tumor makes a tumor look like T3 stage on MRI when in fact, following surgical specimen examining the surgical resection piece is actually a T2 stage [48].…”

Section: Local Staging In Rectal Cancer Using Mrimentioning

confidence: 99%

The Utility of Magnetic Resonance Imaging in the Multidisciplinary Treatment of Patients with Rectal Cancer

Hălmaciu¹,

Andrei²,

Russu³

et al. 2023

Current Topics in Colorectal Surgery

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Rectal cancer is one of the most common types of cancer in both men and women. In recent years, the importance of magnetic resonance imaging (MRI) has greatly increased in the multidisciplinary treatment of patients with rectal cancer. MRI has a particularly important role in the most accurate preoperative staging of these patients, both in terms of assessing the local invasion of the tumor and in terms of assessing the status of pelvic lymph nodes. Many patients with rectal cancer, especially those in the advanced stage of the disease, in the preoperative period undergo neoadjuvant radio chemotherapy. The evaluation of the clinical response of these patients to neoadjuvant therapy is of crucial importance both in terms of personalized treatment and in terms of their prognosis. In this regard, MRI has its clearly defined role at present in evaluating the efficacy of neoadjuvant therapy, as well as in postoperative follow-up.

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Imaging in Colorectal Cancer

Cited by 5 publications

References 27 publications

Assessment of T and N staging with MRI₃T in lower and middle rectal cancer and impact on clinical strategy

Assessment of T and N staging with MRI₃T in lower and middle rectal cancer and impact on clinical strategy

Value of 3Tesla MRI in the preoperative staging of mid‐low rectal cancer and its impact on clinical strategies

The Utility of Magnetic Resonance Imaging in the Multidisciplinary Treatment of Patients with Rectal Cancer

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Imaging in Colorectal Cancer

Cited by 5 publications

References 27 publications

Assessment of T and N staging with MRI3T in lower and middle rectal cancer and impact on clinical strategy

Assessment of T and N staging with MRI3T in lower and middle rectal cancer and impact on clinical strategy

Value of 3Tesla MRI in the preoperative staging of mid‐low rectal cancer and its impact on clinical strategies

The Utility of Magnetic Resonance Imaging in the Multidisciplinary Treatment of Patients with Rectal Cancer

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Product

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Assessment of T and N staging with MRI₃T in lower and middle rectal cancer and impact on clinical strategy

Assessment of T and N staging with MRI₃T in lower and middle rectal cancer and impact on clinical strategy