Initial data from North America shows reduction in lung cancer-related mortality following the use of CT screening. • Staging with TNM 7 has replaced TNM 6 based on evidence-based outcomes reflecting advances in diagnosis and treatment. • CT remains the workhorse for initial diagnostic imaging in lung cancer; however, the uses for positron emission tomography (PET)-CT are ever increasing with greater sensitivity and specificity for staging. • Endoscopic ultrasound-guided nodal sampling via the airways and oesophagus is replacing the need for surgical mediastinal sampling and preventing unnecessary thoracotomies. • Ultrasound-guided sampling of neck nodes should be considered in those patients with mediastinal adenopathy. • Knowledge of potential surgical procedures and their imaging features is vital for reporting radiologists in order to recognize the potential complications. • Stereotactic body radiotherapy-associated changes include ground-glass opacity, consolidation and fibrosis. PET-CT is a helpful adjunct in the follow-up of these patients. • Radiofrequency ablation, cryoablation and microwave ablation are promising new advances in treatment for those patients unsuitable for surgery, although outcomes remain less favourable.Abstract. Lung cancer-related morbidity has a significant impact on the health economy with a 5-year survival rate of 7-9%. Promising early results have been reported in the use of CT screening to reduce mortality. Significant advances have developed in diagnostic imaging with the ever increasing use of positron emission tomography-CT. Nonsurgical invasive sampling methods have been introduced including the use of endoscopic ultrasound-guided needle aspiration. This has been accompanied by advances in surgical techniques, radiotherapy regimes and chemotherapeutic agents. Treatment with curative intent has also increased the role of follow-up imaging, for which regimes are variable between centres and countries. This article aims to review the current evidence with regard to screening, diagnosis, treatment and follow-up.