Imaging of a Coronary Artery Stent Implantation Within an Isolated Human Heart

Eggum, Julianne H.; Howard, Stephen A.; Goff, Ryan P.; Iaizzo, Paul A.

doi:10.1007/s12265-011-9322-y

Cited by 7 publications

(5 citation statements)

References 2 publications

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“…Once a surgical plane of anaesthesia is sustained, a medial sternotomy is performed and a standard cardioplegia solution is rapidly administered (at ~150 mmHg via the aortic cannula) to depolarise the heart. Then, the isolated heart is reanimated using previously published Visible Heart ® methodologies [3][4][5][6][7] . Briefly, the great vessels of the heart are cannulated and attached to the Visible Heart ® apparatus.…”

Section: What Is the Visible Heart ® Laboratory?mentioning

confidence: 99%

Coronary bifurcations as you have never seen them: the Visible Heart® Laboratory bifurcation programme

Burzotta¹,

Cook²,

Iaizzo³

et al. 2015

EuroIntervention

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The Visible Heart® Laboratory is an original experimental laboratory in which harvested animal hearts are resuscitated and connected to a support machine in order to beat outside the animal body. Resuscitated animal hearts may be exposed to various types of endovascular intervention under full, multimodality inspection. This unique experimental setting allows the performance of percutaneous coronary intervention (PCI) in a setting which resembles a standard catheterisation laboratory set-up, and contemporaneously allows unique multimodality imaging. For these reasons, the performance of PCI on bifurcations in the Visible Heart® Laboratory may improve the knowledge of the dynamic stent deformations and stent-vessel wall interactions associated with the different steps of the various techniques for bifurcation stenting. Furthermore, the collected images may also serve as a novel educative resource for physicians. The performance of bifurcation stenting in the Visible Heart® Laboratory is a promising experimental setting to gain novel information regarding any existing or future PCI technique to treat coronary bifurcations.

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Section: What Is the Visible Heart ® Laboratory?mentioning

confidence: 99%

Coronary bifurcations as you have never seen them: the Visible Heart® Laboratory bifurcation programme

Burzotta¹,

Cook²,

Iaizzo³

et al. 2015

EuroIntervention

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“…We generated renderings for both the arterial and venous vasculatures, the right and left heart blood volumes, and the lungs (Figure 4A). Additionally, from the scans obtained from this patient's isolated perfusion-fixed heart, 17 we again modeled the myocardium (in higher resolution) as well as the clinically implanted devices; various computational cuts could be made to optimally visualize different planes within these computational models. For relative comparisons, external and 4-chamber views of a healthy human heart are shown next to this patient's heart for scale (Figures 4B and 4C).…”

Section: D Modeling and Printingmentioning

confidence: 99%

First Successful Open-Heart Surgery Utilizing Cross-Circulation in 1954

Iles

Holm

Calvin

et al. 2020

The Annals of Thoracic Surgery

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“…Despite advances in diagnostic and therapeutic management of breast cancer, progress in dealing with its early stage detection and treatment is still ambiguous. , According to the literature in 2015, estimated deaths due to breast cancer was 90,800 in the European Union (EU) and 40,290 in the USA. − Several clinical studies demonstrate that screening a woman’s breast using mammography can help to identify early indications of breast cancer. , Mammography is important for the early recognition of the disease, although sometimes the results are suspicious or non-detectable with patients with early-stage breast cancer or small lesion. − An additional analysis includes a breast core biopsy under imaging guidance by obtaining a tissue from a suspected breast cancer region (lesion). When the area of the suspicious lesion is small, it is possible to remove the entire lesion during image-guided biopsy.…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Breast Tissue Marker Clip

Zada

Gallimidi

Schlesinger-Laufer

et al. 2020

ACS Appl. Bio Mater.

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Biodegradable soft tissue biopsy clips have been developed as implants with the potential to serve as visual markers for regions suspected to contain tumor growth in the breast. These clips are multidimensional tissue markers with better biocompatibility and imaging features. The clips were prepared using biodegradable polymers, poly(L-lactide-co-ε-caprolactone) and methoxy polyethylene glycol-co-L-lactide, that contain iodixanol or barium sulfate as contrast agents; they are further coated with hyaluronic acid or sodium alginate hydrogels. The clips were visible by imaging modalities such as mammography, ultrasound, and magnetic resonance imaging after implantation in Sprague− Dawley rats. The clips stayed intact in the implantation cavity of the animal for more than 3 months with unpretentious changes in their lengths and morphology. The histopathological examination of implanted clips revealed no signs of systemic toxicity in the rats. Overall, the interpretation of the results reveals that the developed clips can be a potential replacement for metal-based markers.

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Imaging of a Coronary Artery Stent Implantation Within an Isolated Human Heart

Cited by 7 publications

References 2 publications

Coronary bifurcations as you have never seen them: the Visible Heart® Laboratory bifurcation programme

Coronary bifurcations as you have never seen them: the Visible Heart® Laboratory bifurcation programme

First Successful Open-Heart Surgery Utilizing Cross-Circulation in 1954

Biodegradable Breast Tissue Marker Clip

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