Imaging of Chronic Recurrent Multifocal Osteomyelitis

Jurriaans, Erik; Singh, Nina; Finlay, Karen; Friedman, Lawrence

doi:10.1016/s0033-8389(05)70279-7

Cited by 58 publications

(60 citation statements)

References 54 publications

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“…Involvement of the clavicle is characteristic because it is a site that is seldom affected by hematogenous osteomyelitis. The spinal involvement seen in this patient is rare, and in a review of 35 cases of 157 lesions, only 3 % were present in vertebral bodies [8]. However, initial presentation with isolated vertebra plana or other primary spinal involvement has been previously described in children, although not in adults [9].…”

Section: Discussionmentioning

confidence: 56%

Chronic recurrent multifocal osteomyelitis with an atypical presentation in an adult man

et al. 2015

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We present the case of a 33-year-old man with no significant medical history who developed right scapular pain, left-sided sacroiliac joint pain, and lower back pain, and was eventually diagnosed with chronic recurrent multifocal osteomyelitis (CRMO). Imaging demonstrated multiple scattered T2-hyperintense lesions on MRI at the spine and the left SI joint, some of which progressed and one regressed in size on follow-up. Histopathology demonstrated only non-specific chronic inflammation compatible with CRMO. No evidence of infectious organisms or neoplastic processes was found. The pain was relapsing and remitting in nature. Laboratory investigations were notable for no evidence of hematologic malignancy or infection, but only a mild increase in alkaline phosphatase. This case highlights that CRMO, despite being thought of as a childhood-onset disease, can present in adults as well, and also provides illustrative examples of imaging and histological findings.

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Section: Discussionmentioning

confidence: 56%

Chronic recurrent multifocal osteomyelitis with an atypical presentation in an adult man

et al. 2015

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“…These appearances are typical of CRMO. other areas throughout the skeleton including the spine, pelvis, sacroiliac joints, ribs, sternum, scapulae, metatarsals, metacarpals, tarsal bones, phalanges and mandible (2).…”

Section: Discussionmentioning

confidence: 99%

“…With healing, progressive sclerosis is usually seen around the lytic lesion with associated hyperostosis (3). During relapses, new lytic lesions appear with periosteal reaction resulting in bone thickening (2,3). Spinal lesions are characterised by erosion of the vertebral end plate with adjacent sclerosis.…”

Section: Discussionmentioning

confidence: 99%