Imaging of M^|^eacute;ni^|^egrave;re's Disease after Intravenous Administration of Single-dose Gadodiamide: Utility of Subtraction Images with Different Inversion Time

Abstract

For the separate visualization of endolymph, perilymph, and bone on a single image after intravenous injection of single-dose gadodiamide, we fused gray-scale inverted positive endolymph (PEI) with native positive perilymph (PPI) images, that is, we subtracted PEI from PPI. Subtraction signiˆcantly improved the contrast noise ratio between endolymph and perilymph and the subjective visibility score for endolymphatic space. The 24 patients with the suspect of M áeni àere's disease were included.

The Technical and Clinical Features of 3D-FLAIR in Neuroimaging

“…11). 37,38,[101][102][103][104][105][106][107][108] In summary, 3D-FLAIR using VFA-TSE has several unique advantages for clinical neuroimaging as shown below: 1) Thinner slices and multi-planar reformation capability, 2) Higher flow sensitivity, 3) High sensitivity to subtle T 1 changes in fluid, 4) Free from CSF inflow artifacts, 5) Reasonable scan time, and 6) A 3D dataset that allows computer-aided analysis. Familiarity with these features of 3D-FLAIR imaging and proper use of 3D-FLAIR are important in order for radiologists to obtain useful information for patient management.…”

Detection and Grading of Endolymphatic Hydrops in Menière Disease Using MR Imaging

“…Since the first publication of MR imaging visualization of EH in an animal study in 2001 15 and MR imaging demonstration of EH in patients with MD following intratympanic injection in 2007, 16 numerous studies have tried to visualize EH by using different routes of administration of contrast media, such as intratympanic 16 versus intravenous [17][18][19][20] and by altering intravenous dosage regimens (single, 13,17 24 and 3D-IR sequences. 13 On the basis of previous demonstration of the feasibility to separate the endoand perilymphatic space 24 hours after intratympanic gadolinium injection by a 3D-IR sequence 13 and the observation that perilymphatic enhancement occurs 4 hours after intravenous contrast administration, 21,25 our protocol comprised a 3D-IR sequence obtained 4 hours following intravenous injection of contrast media.…”

MR Imaging of Ménière’s Disease after Combined Intratympanic and Intravenous Injection of Gadolinium using HYDROPS2

“…11 In the present study, there was no significant motion between hT 2 W-3D-FLAIR and MRC, but subtraction is susceptible to motion be- tween scans. 3,13 This problem might be overcome by the registration program available on most 3D workstations.…”

“…[3][4][5][6] The IT method usually provides higher contrast than the IV method and can predict the intralabyrinthine distribution of intratympanically injected gentamicin and steroids. 7,8 However, IT administration of GBCM is off-label use and requires puncture of the tympanic membrane.…”