Imaging of Small Renal Masses before and after Thermal Ablation

Lum, Mark; Shah, Shreena; Durack, Jeremy C.; Nikolovski, Ines

doi:10.1148/rg.2019190083

Cited by 22 publications

(11 citation statements)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Primary TE was defined as the absence of new contrast enhancement and/or tumor enlargement at the first control. Homogenous, smooth, and low-level enhancement may be seen on post-ablation imaging without corresponding to recurrence [20]. This was assessed by contrast-enhanced CT or MRI between 1 week after the procedure [10] to 6 months after [12].…”

Section: Analysis Techniquementioning

confidence: 99%

See 1 more Smart Citation

Local recurrence and other oncologic outcomes after percutaneous image-guided tumor ablations on stageT1b renal cell carcinoma: a systematic review and network meta-analysis

Cazalas

Jambon

Coussy

et al. 2021

International Journal of Hyperthermia

View full text Add to dashboard Cite

Objective: A systematic review of clinical trials on thermal ablation of T1b RCC was conducted to assess oncologic outcomes of those procedures. The primary endpoint was the rate of local recurrence. Secondary endpoints included technical efficacy, progression to metastatic disease, cancer-specific mortality, complications and renal function decrease. Methods: PubMed (MEDLINE) and Embase databases were searched in June 2020 for eligible trials following the PRISMA selection process. Prevalence of local recurrence and per procedural major adverse effects were calculated using double arcsine transformation and a random-effects model. Results: Nine clinical trials (all retrospective) involving 288 patients with T1b renal clear cell carcinoma treated with either percutaneous microwave ablation, cryoablation or radiofrequency ablation were analyzed. Using a random-effects model, the overall prevalence of local recurrence following percutaneous ablation was 0.08 (0.04-0.14; p ¼ 0.05). Primary technical efficacy was 226/263 (86%) patients and secondary technical efficacy was 247/263 (94%). Overall, 10/176 (6%) patients presented metastatic locations following the ablation. Major adverse effects prevalence was 0.09 (0.06-0.14; p ¼ 0.05). Conclusions: Thermal ablations are feasible, safe, and effective to treat T1b renal clear cell carcinoma. More trials are necessary to determine the rate of the evidence of the benefit. HIGHLIGHTSThermal ablations are feasible and safe to treat T1b renal clear cell carcinoma. Oncologic outcomes appear to be very good on both local control and distant progression. Due to small number and heterogeneity of studies more trials are necessary to determine the rate of the evidence of the benefit.

show abstract

Section: Analysis Techniquementioning

confidence: 99%

“…LR was defined as a new nodular or irregular enhancement within the ablation zone or enlargement of the ablated tumor in a patient after TE was obtained [20]. LRFS was evaluated depending on studies at 3, 5 or 10 years.…”

Section: Analysis Techniquementioning

confidence: 99%

Local recurrence and other oncologic outcomes after percutaneous image-guided tumor ablations on stageT1b renal cell carcinoma: a systematic review and network meta-analysis

Cazalas

Jambon

Coussy

et al. 2021

International Journal of Hyperthermia

View full text Add to dashboard Cite

show abstract

“…With the development of endoscopes and auxiliary equipment, colonoscopy has made great progress in the diagnosis and treatment of colorectal diseases [ 6 ]. Colonoscopy can not only make correct judgments on various colorectal diseases but also becomes more and more important in terms of treatment [ 7 ]. In the past, the diagnosis of colorectal diseases mainly relied on barium enema, but the accuracy was not high, smaller lesions were difficult to find, and sometimes larger lesions were difficult to diagnose [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Ultrasound Image Features under Decomposition Algorithm to Analyze the Nursing Intervention on Patients with Colon Polyps Undergoing Endoscopic Resection

Wang

Zhao

et al. 2021

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

Based on the ultrasonic imaging and endoscopic resection of the intelligent segmentation algorithm, this study is aimed at exploring whether nursing intervention can promote the good recovery of patients with colon polyps, hoping to find a new method for clinical treatment of the colon polyps. Patients with colon polyps were divided into an experimental group (fine nursing) and a control group (general nursing). The colonoscopy polyp ultrasound image was preprocessing to select the seed points and background points. The random walk decomposition algorithm was applied to calculate the probability of each marked point, and then, the marked image was outputted. The accuracy of the intelligent segmentation algorithm was 81%. The incidence of complications in the experimental group was 4.83%, which was lower than 16.66% in the control group, and the difference was statistically obvious ( P < 0.05 ). Perioperative refined nursing intervention for colon polyp patients undergoing endoscopic electrosurgical resection can decrease postoperative adverse reactions; reduce postoperative mucosal perforation, blood in the stool, abdominal pain, and small bleeding; lower the incidence of postoperative complications; and allow patients to recover quickly, enhancing the life comfort of patient.

show abstract

“…The absence of enhancement on contrast-based studies has been shown to be reliable in excluding viable carcinoma in ablated tumors ( 13 ). However, the presence of enhancement, particularly weak contrast uptake, is not pathognomonic for residual or recurrent disease and may represent inflammatory changes ( 14 ). Our results highlight that of those patients undergoing extirpative surgery, 25% had only necrosis or fibrosis on final pathology.…”

Section: Discussionmentioning

confidence: 99%

Management of Residual or Recurrent Disease Following Thermal Ablation of Renal Cortical Tumors

Loloi

Shingleton

Nakada

et al. 2020

jkcvhl

View full text Add to dashboard Cite

Management of residual or recurrent disease following thermal ablation of renal cortical tumors includes surveillance, repeat ablation, or surgical extirpation. We present a multicenter experience with regard to the management of this clinical scenario. Prospectively maintained databases were reviewed to identify 1265 patients who underwent cryoablation (CA) or radiofrequency ablation (RFA) for enhancing renal masses. Disease per-sistence or recurrence was classified into one of the three categories: (i) residual disease in ablation zone; (ii) recurrence in the ipsilateral renal unit; and (iii) metastatic/extra-renal disease. Seventy seven patients (6.1%) had radiographic evidence of disease persistence or recurrence at a median interval of 13.7 months (range, 1–65 months) post-ablation. Distribution of disease included 47 patients with residual disease in ablation zone, 29 with ipsilateral renal unit recurrences (all in ablation zone), and one with metastatic disease. Fourteen patients (18%) elected for surveillance, and the remaining underwent salvage ablation (n = 50), partial nephrectomy (n = 5), or radical nephrectomy (n = 8). Salvage ablation was successful in 38/50 (76%) patients, with 12 failures managed by observation (3), tertiary ablation (6), and radical nephrectomy (3). At a median follow-up of 28 months, the actuarial cancer-specific survival and overall survival in this select cohort of patients was 94.8 and 89.6%, respectively.

show abstract

Imaging of Small Renal Masses before and after Thermal Ablation

Cited by 22 publications

References 72 publications

Local recurrence and other oncologic outcomes after percutaneous image-guided tumor ablations on stageT1b renal cell carcinoma: a systematic review and network meta-analysis

Local recurrence and other oncologic outcomes after percutaneous image-guided tumor ablations on stageT1b renal cell carcinoma: a systematic review and network meta-analysis

Ultrasound Image Features under Decomposition Algorithm to Analyze the Nursing Intervention on Patients with Colon Polyps Undergoing Endoscopic Resection

Management of Residual or Recurrent Disease Following Thermal Ablation of Renal Cortical Tumors

Contact Info

Product

Resources

About