Imaging of the anterior segment in glaucoma

See, Jovina

doi:10.1111/j.1442-9071.2009.02081.x

Cited by 41 publications

(39 citation statements)

References 36 publications

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“…A recent study suggested that gonioscopy should be still considered the goldstandard method in detecting PAC and it cannot be replaced by the anterior segment imaging even if both AS-OCT and UBM can be useful in several circumstances (Barkana et al, 2007;Dorairaj et al, 2012;Friedman et al, 2012;Ishikawa et al, 2000;McKee et al, 2013;Pavlin et al, 1992;Pekmezci et al, 2009;Quek et al, 2011;See, 2009). …”

Section: Anterior Segment Imagingmentioning

confidence: 95%

New findings in the diagnosis and treatment of primary angle-closure glaucoma

Marchini¹,

Chemello²,

Berzaghi³

et al. 2015

Progress in Brain Research

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Section: Anterior Segment Imagingmentioning

confidence: 95%

New findings in the diagnosis and treatment of primary angle-closure glaucoma

Marchini¹,

Chemello²,

Berzaghi³

et al. 2015

Progress in Brain Research

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“…found no statistical difference between the results of two examiners: the 95% intra-observer limits of agreement were within ±5°, with ICC (intra-class correlation coefficient) below 0.75. The EAS-1000 shows also good intra-observer repeatability, with a 95% inter-observer limits of agreement within ±6° and an ICC around 0.75 in healthy subjects [109]. The Pentacam seems to have the same intra-observer repeatability, with relative repeatability of 5.68% for volume, 3.07% for depth and 14.41% for angle [111].…”

Section: Scheimpflug Photographymentioning

confidence: 67%

“…Anterior chamber depth can be measured locating manually the surface of the posterior cornea and the anterior surface of crystalline lens [103,109].…”

Section: Scheimpflug Photographymentioning

confidence: 99%

Angle Closure Glaucoma: Pathogenesis and Evaluation. A Review

Fea¹,

Bertaina²,

Consol³

et al. 2012

J Clinic Experiment Ophthalmol

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Pupillary block is the most common mechanism responsible for angle closure [9], but the anatomical configuration which causes a plateau iris may be a more common mechanism than was previously thought. Pupillary block mechanismIn pupillary block, the resistance to aqueous flow from the posterior to anterior chamber is at the level of the pupil, creating a pressure gradient that causes forward bowing of the peripheral iris and closure of the angle [10,11].Aqueous humor flow from the posterior chamber into the anterior chamber is regulated by a differential pressure between the anterior and the posterior chamber. This pressure differential may increase greatly when the dimensions of the iris-lens channels are changed. As this pressure increment increases, the iris becomes more convex and can close angle.Extreme anterior iris-bulging, iris bombé would be expected with pressure differentials of 10-15 mm Hg [12]. The variables that influence the flow through the ''pinch region'' (iris-lens channels) and influence the pressure differential and related iris contour have been studied extensively [12][13][14][15][16].Changes in pupillary size, increased channel length and decreased height, movement of the iris insertion posteriorly or of the lens anteriorly, were associated with an expected increase in the pressure differential. Other variables exist and interact to determine the iris contour, including eye size, especially the dimensions of the anterior segment, lens size and position, iris stroma and iris musculature characteristics, ciliary body anatomy, and physiologic parameters including aqueous humor flow rate, facility of outflow, vitreousaqueous fluid flow, and the effects of accommodation and blinking [9]. AbstractPrimary open angle glaucoma (PACG) is a major cause of blindness especially in Asia. The pathogenesis of this condition has been widely investigated. Traditionally gonioscopy is the method of choice for the esamination of patients considered to be at risk for angle closure, but it is a rather invasive procedure and it is reported to be primarily used by glaucoma specialists. Recently newer ultrasound and optical methods for the evaluation of the anterior chamber angle have been introduced in the clinical practice, with distinct advantages and disadvantages both compared to each other and to gonioscopy. This review will address the pathogenesis of PACG, the use of gonioscopy and will evaluate the newer methods of angle examination.

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“…Ayr›ca görülebilir ›fl›k kulland›¤›ndan miyozisi uyarmakta ve aç›n›n oldu¤undan genifl görünmesine yol açabilmek-tedir (12).…”

Section: Tart›flmaunclassified

Quantitative Analysis of Anterior Chamber Angle by Ultrasound Biomicroscopy in a Healthy, Young Male Population

Salcan¹,

Aykan²,

Colakoglu³

et al. 2010

tod

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ÖzetAmaç: Bu çal›flmada oküler ve sistemik bir hastal›¤› olmayan, sa¤l›kl›, genç, erkek popülasyonda ultrason biyomikroskopi yöntemi ile ön kamara aç›s›na ait nicel de¤erlerin saptanmas› amaçlanm›flt›r. Gereç ve Yöntem:Otuzsekiz erkek olguya ait 38 göz çal›flmaya dahil edilmifltir. Tüm olgular›n ultrason biyomikroskopi muayeneleri standart koflullar sa¤lanarak, ayn› kifli taraf›ndan yap›lm›flt›r. Ultrason biyomikroskopi muayenesinde ön segmentin aksiyel görüntüleri ile temporal kadranda aç›n›n radyal kesit görüntüleri al›nd›. Aç› parametreleri UBM Pro2000® yaz›l›m› ile elde edildi. Sonuçlar:Olgular›n tümü erkek olup, ortalama yafl 21,3±0,9 (21-26 ) y›l olarak saptanm›flt›r. Ortalama santral aksiyel ön kamara derinli¤i: 3.25 ± 0.26 mm, aç› sonlanmas› alan›: 0,167±0,020 mm 2 , aç› aç›kl›¤› mesafesi 250: 0,174±0,032 mm, aç› aç›kl›¤› mesafesi 500: 0.223±0.013 mm ve sklera mahmuzu-iris kökü aras› mesafe: 0,269±0,052 mm olarak saptanm›flt›r. Tart›flma: Ultrason biyomikroskopisi ön segment yap›lar› hakk›nda nitel ve nicel bilgiler vermektedir. Ön kamarada aç›-ya ait say›sal normal de¤erlerin elde edilmesi bize aç› alan›n›n objektif incelenmesi ve takibinde yard›mc› olabilecektir. Bu çal›flma ile sa¤l›kl›, genç, erkek popülasyona ait saptad›¤›m›z say›sal veriler, ülkemizde daha sonra yap›labilecek ça-l›flmalar için referans de¤erler olarak kullan›labilirler. (TOD Dergisi 2010; 40: 194-8) Anahtar Kelimeler: Ultrason biyomikroskopi, ön kamara aç›s›, Ön kamara aç› parametreleri Summary Purpose: The aim of this study is to determine the quantitative values of anterior chamber angle by means of ultrasound biomicroscopy in a young healthy male population without ocular and systemic diseases. Material and Method:In this study, 38 eyes of 38 male subjects were included. Ultrasound biomicroscopy examinations were always performed by the same person under standardized environment and conditions. At each session, axial images of anterior chamber and radial sections of the angle at the lateral quadrant were taken. Angle parameters were obtained by UBM Pro2000® software. Results: The mean age of the subjects was 21.3±0.9 years, ranging from 21 to 26 years and all of the subjects were male. It was observed that the mean central axial anterior chamber depth was 3.25±0.26 mm, mean angle recess area was 0.167±0.020 mm 2 , mean angle opening distance at 250 microns was 0.174±0.032 mm, mean angle opening distance at 500 microns was 0.223±0.013 mm, and the mean scleral spur-iris root distance was 0.269±0.052 mm in our subjects. Discussion: Ultrasound biomicroscopy gives either qualitative or quantitative information about anterior segment structures. Determination of the quantitative normal values of anterior chamber angle may help us to evaluate and follow this area objectively. The quantitative data belonging to healthy young male patients provided by this study may be used as reference values for future studies that can be performed in our country. (TOD Journal 2010; 40: 194-8)

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Imaging of the anterior segment in glaucoma

Cited by 41 publications

References 36 publications

New findings in the diagnosis and treatment of primary angle-closure glaucoma

New findings in the diagnosis and treatment of primary angle-closure glaucoma

Angle Closure Glaucoma: Pathogenesis and Evaluation. A Review

Quantitative Analysis of Anterior Chamber Angle by Ultrasound Biomicroscopy in a Healthy, Young Male Population

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