“…While UD has been reported as a congenital abnormality, most cases are acquired and usually present in the third to fifth decade. 2,4 Causal factors include infection of the periurethral (Skene's) glands, urethral injury during childbirth, previous surgery and repetitive trauma. 5 Infection of these glands has been postulated as a cause of diverticulum formation, 6 , and the most frequent localization in the middle or distal third of the urethra, where the number of glands increased, supports this hypothesis.…”