Imaging Strategies for Localization of ACTH-Secreting Tumors

Nieman, Lynnette K.; Gharib, Ahmed M.

doi:10.1007/978-3-319-45950-9_7

Cited by 1 publication

(4 citation statements)

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“…41 The measurement is usually done by radioimmunoassay (RIA) or enzyme-linked immunoassay (ELISA), with RIA being highly sensitive, but prone to operation procedures, and ELISA generally producing more reliable measurements. 9,41,53…”

Section: Methodsmentioning

confidence: 99%

“…Typically, cortisol is measured by immunoassays, such as RIA or ELISA. 15,54,80 There is poor standardization of the assays used to measure cortisol, gas and liquid chromatography mass-spectrometry (GC-MS and LC-MS) are more reliable compared with immunoassays regarding accuracy, sensitivity, and specificity. 15…”

Section: Cortisolmentioning

confidence: 99%

“…Typical assays used for the measurement are 2-site immunometric assays or RIA, although there is inadequate standardization of the assays used to measure ACTH. 53,80 Immunometric assays show a better sensitivity compared with RIA and are preferred for the measurement of ACTH. 75…”

Section: Adrenocorticotropic Hormonementioning

confidence: 99%

“…39 Blood cortisol levels are measurable either in plasma or, more frequently, in serum and may be comparable. 15,54 Furthermore, total cortisol levels may be decreased in individuals with hypoproteinaemia because cortisol circulates predominantly bound to albumin and corticosteroid-binding protein, respectively. Thus, total cortisol levels must be interpreted carefully.…”

Section: Cortisolmentioning

confidence: 99%

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