Imidazole Pretreatment of Oil Palm Empty Fruit Bunches for Ethanol and Succinic Acid Co-production by Saccharomyces cerevisiae and Pichia stipitis

Metabolic engineering in lignocellulose biorefining for high-value chemicals: recent advances, challenges, and outlook for enabling a bioeconomy

“…For instance, succinic acid has been successfully produced from various LCB sources such as sugarcane bagasse, corn stover, oil palm trunk, empty fruit bunches, grape pomace, straws, and grasses. Microbes such as Actinobacillus succinogenes, Basfia succiniciproducens, and Saccharomyces cerevisiae have been utilized to produce high titers of succinic acid, ranging from 1.07-40.2 g/L (Bu et al, 2019;Bukhari et al, 2020;Lo et al, 2020;Filippi et al, 2021;Vallecilla-Yepez et al, 2021;Jokodola et al, 2022;Lee et al, 2022;Bukhari et al, 2023;Robertiello et al, 2023;Zevallos Torres et al, 2023). Lactic acid, another chemical, is produced through microbial processes involving Lactobacillus spps, Bacillus coagulans, and Rhizopus oryzae with various feedstocks such as corn stover, straw, sugarcane bagasse and molasses, beechwood, pine, and grasses.…”