Imidazole Ring-Opened DNA Purines and Their Biological Significance

Tudek, Barbara

doi:10.5483/bmbrep.2003.36.1.012

Search citation statements

Order By: Relevance

Paper Sections

Select...

Reactive Oxygen Species (Ros) In Living Cells1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2003

2021

Publication Types

Select...

Article5

Book1

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 46 publications

(1 citation statement)

References 178 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a minor oxidized product of guanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine (Fapy-G, Figure 10) can be formed by H 2 O 2 and metal ions [63,71]. Mutagenicity of Fapy-G is low [72]; however, a related product, methyl-Fapy-G formation, is a lethal lesion [73]. Furthermore, a theoretical study suggested that the formation of Fapy-G contributes to mutation [74].…”

Section: Reactive Oxygen Species (Ros) In Living Cellsmentioning

confidence: 99%

Biomolecules Oxidation by Hydrogen Peroxide and Singlet Oxygen

Hirakawa¹

2018

Reactive Oxygen Species (ROS) in Living Cells

View full text Add to dashboard Cite

Hydrogen peroxide (H 2 O 2) and singlet oxygen (1 O 2) are important reactive oxygen species (ROS) for biological and medicinal fields. Oxidation processes of chemical materials by molecular oxygen are important H 2 O 2 source, whereas photochemical reaction is important for 1 O 2 production. Reactivity and biomolecule damage by these ROS depend on the surrounding conditions and targeting molecules. In this chapter, production mechanisms of H 2 O 2 and 1 O 2 , biomolecule oxidation by these ROS, their detection methods, and production control of 1 O 2 are briefly reviewed.

show abstract